Mediterraneibacter gnavus strain AM32-6

Gram-positiveCocciNon-motileAnaerobic

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Mediterraneibacter

Description

Mediterraneibacter gnavus strain AM32-6 is a Gram-positive, non-motile coccus that thrives in the anaerobic environment of the intestinal microflora of Homo sapiens. This bacterium is classified as a chemoheterotroph, deriving its energy from organic compounds rather than photosynthesis or inorganic substances. Its optimal growth temperature is 37°C, placing it within the mesophilic temperature range, which is typical for many bacteria residing in the human gut. M. gnavus strain AM32-6 possesses a single replicon and does not form spores, indicating a stable genetic structure and a reliance on consistent environmental conditions for survival. Notably, this strain has been associated with inflammatory bowel disease (IBD), suggesting a potential pathogenic role in human health. The presence of this bacterium in the gut may contribute to dysbiosis, which is characterized by an imbalance in the microbial community and can exacerbate IBD symptoms. The strain's flagella presence, although it does not exhibit mobility, may play a role in its adherence to intestinal surfaces, contributing to its ecological niche within the gut microbiome. Overall, the existence of Mediterraneibacter gnavus strain AM32-6 underscores the complex interplay between gut microbiota and human health, particularly in relation to inflammatory conditions such as IBD. Further research into its specific mechanisms of action could provide deeper insights into its role in gastrointestinal health and disease.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusMediterraneibacter
SpeciesMediterraneibacter gnavus
Strainstrain AM32-6

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Mediterraneibacter gnavus strain AM32-6
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatAnimal intestinal microflora
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Mediterraneibacter gnavus strain AM32-6 AM32-6.Scaf108, whole

Gene Summary

Adenine Count

1102643 bp

Thymine Count

1114709 bp

Guanine Count

807608 bp

Cytosine Count

825890 bp

Genome Length

3851554 bp

Protein-coding Genes

3423 genes

Non-Coding Genes

231 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
23s rrna (adenine(2058)-n(6))-methyltransferase erm(b)DW812_18710Not AvailablePositive3794099 - 379483628797.2
hypothetical proteinDW812_18715Not AvailablePositive3794841 - 37949544111.19
xre family transcriptional regulatorDW812_18720Not AvailablePositive3795198 - 37954379160.96
replication protein reprDW812_18725Not AvailablePositive3795832 - 379732257442.5
bifunctional aminoglycoside n-acetyltransferase aac(6')-ie/aminoglycoside o-phosphotransferase aph(2'')-iaDW812_18735Not AvailableNegative3797592 - 379903156858.2
gnat family n-acetyltransferaseDW812_18740Not AvailableNegative3799032 - 379942414996.9
is256 family transposase is256DW812_18745Not AvailableNegative3799551 - 380072345676.4
n-acetylglucosamine-6-phosphate deacetylaseDW812_18755Not AvailableNegative3801105 - 380224741657.5
chorismate--pyruvate lyaseDW812_18760Not AvailableNegative3802360 - 38025366990.51
abc transporter permeaseDW812_18765Not AvailableNegative3802559 - 380329627624.0

Displaying genes 3591 – 3600 of 3654 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Inflammatory bowel disease (ibd)CausesPMC12034673

Displaying health effects 1 – 1 of 1 in total