Mediterraneibacter gnavus strain AM32-6

Gram-positiveCocciNon-motileAnaerobic

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Mediterraneibacter

Description

Mediterraneibacter gnavus strain AM32-6 is a Gram-positive, non-motile coccus that thrives in the anaerobic environment of the intestinal microflora of Homo sapiens. This bacterium is classified as a chemoheterotroph, deriving its energy from organic compounds rather than photosynthesis or inorganic substances. Its optimal growth temperature is 37°C, placing it within the mesophilic temperature range, which is typical for many bacteria residing in the human gut. M. gnavus strain AM32-6 possesses a single replicon and does not form spores, indicating a stable genetic structure and a reliance on consistent environmental conditions for survival. Notably, this strain has been associated with inflammatory bowel disease (IBD), suggesting a potential pathogenic role in human health. The presence of this bacterium in the gut may contribute to dysbiosis, which is characterized by an imbalance in the microbial community and can exacerbate IBD symptoms. The strain's flagella presence, although it does not exhibit mobility, may play a role in its adherence to intestinal surfaces, contributing to its ecological niche within the gut microbiome. Overall, the existence of Mediterraneibacter gnavus strain AM32-6 underscores the complex interplay between gut microbiota and human health, particularly in relation to inflammatory conditions such as IBD. Further research into its specific mechanisms of action could provide deeper insights into its role in gastrointestinal health and disease.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusMediterraneibacter
SpeciesMediterraneibacter gnavus
Strainstrain AM32-6

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Mediterraneibacter gnavus strain AM32-6
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatAnimal intestinal microflora
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Mediterraneibacter gnavus strain AM32-6 AM32-6.Scaf108, whole

Gene Summary

Adenine Count

1102643 bp

Thymine Count

1114709 bp

Guanine Count

807608 bp

Cytosine Count

825890 bp

Genome Length

3851554 bp

Protein-coding Genes

3423 genes

Non-Coding Genes

231 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lrp/asnc family transcriptional regulatorDW812_07180Not AvailableNegative1464412 - 146491218739.7
hydrogenase expression/formation protein hypeDW812_07185Not AvailableNegative1464927 - 146596438022.8
endonuclease iiiDW812_07190Not AvailableNegative1466162 - 146678824150.2
b12-binding domain-containing radical sam proteinDW812_07195Not AvailableNegative1466785 - 146854568959.2
trna adenosine(34) deaminase tadaDW812_07205Not AvailableNegative1468891 - 146937318383.6
hypothetical proteinDW812_07210Not AvailablePositive1469469 - 147028431119.8
deoxyguanosinetriphosphate triphosphohydrolaseDW812_07215Not AvailableNegative1470277 - 147168954611.4
hypothetical proteinDW812_07220Not AvailableNegative1471703 - 147237125892.8
d-ala-d-ala carboxypeptidase vanyDW812_07225Not AvailableNegative1472545 - 147333629988.5
4'-phosphopantetheinyl transferaseDW812_07230Not AvailableNegative1473324 - 147396525419.5

Displaying genes 1591 – 1600 of 3654 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Inflammatory bowel disease (ibd)CausesPMC12034673

Displaying health effects 1 – 1 of 1 in total