Dorea formicigenerans strain AM42-8

Gram-positiveAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Dorea

Description

Dorea formicigenerans strain AM42-8 is a Gram-positive anaerobic bacterium predominantly found in the gut of Homo sapiens. This strain is characterized by its ability to thrive in an oxygen-free environment, which is typical for microorganisms residing in the human gastrointestinal tract. Additionally, D. formicigenerans possesses flagella, allowing for motility in its natural habitat. The genetic makeup of Dorea formicigenerans strain AM42-8 includes a single replicon, indicating a streamlined genomic organization. This trait may contribute to its adaptability and efficiency in nutrient utilization within the gut ecosystem. The strain is cataloged under the accession number QSFS00000000.1, which provides a reference point for genomic and taxonomic studies. The presence of Dorea formicigenerans within the human gut microbiome highlights its potential role in human health. As an anaerobe, it may contribute to the fermentation of dietary fibers and production of short-chain fatty acids, which are beneficial for gut health and may influence metabolic processes within the host. Understanding the characteristics and functions of this strain can provide insights into the complex interactions between gut microbiota and human health, emphasizing the importance of maintaining a balanced microbiome for optimal physiological function.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusDorea
SpeciesDorea formicigenerans
Strainstrain AM42-8

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgut
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Dorea formicigenerans strain AM42-8 AM42-8.Scaf41, whole genome

Gene Summary

Adenine Count

1045947 bp

Thymine Count

955694 bp

Guanine Count

733057 bp

Cytosine Count

617338 bp

Genome Length

3352156 bp

Protein-coding Genes

3009 genes

Non-Coding Genes

65 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
homoserine dehydrogenaseDW924_13370Not AvailablePositive2801551 - 280277144843.0
aspartate kinaseDW924_13375Not AvailablePositive2802787 - 280399543902.9
helix-turn-helix domain-containing proteinDW924_13380Not AvailableNegative2804020 - 280442715905.0
cyth domain-containing proteinDW924_13385Not AvailableNegative2804569 - 280501217274.4
dj-1 family proteinDW924_13390Not AvailablePositive2805119 - 280568220426.5
trigger factorDW924_13395Not AvailablePositive2805835 - 280712148117.2
atp-dependent clp endopeptidase proteolytic subunit clppDW924_13400Not AvailablePositive2807155 - 280773621228.4
atp-dependent clp protease atp-binding subunit clpxDW924_13405Not AvailablePositive2807775 - 280903446526.9
endopeptidase laDW924_13410Not AvailablePositive2809098 - 281144388351.2
yiha family ribosome biogenesis gtp-binding proteinDW924_13415Not AvailablePositive2811445 - 281203522332.2

Displaying genes 2561 – 2570 of 3074 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.