Dorea formicigenerans strain AM42-8

Gram-positiveAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Dorea

Description

Dorea formicigenerans strain AM42-8 is a Gram-positive anaerobic bacterium predominantly found in the gut of Homo sapiens. This strain is characterized by its ability to thrive in an oxygen-free environment, which is typical for microorganisms residing in the human gastrointestinal tract. Additionally, D. formicigenerans possesses flagella, allowing for motility in its natural habitat. The genetic makeup of Dorea formicigenerans strain AM42-8 includes a single replicon, indicating a streamlined genomic organization. This trait may contribute to its adaptability and efficiency in nutrient utilization within the gut ecosystem. The strain is cataloged under the accession number QSFS00000000.1, which provides a reference point for genomic and taxonomic studies. The presence of Dorea formicigenerans within the human gut microbiome highlights its potential role in human health. As an anaerobe, it may contribute to the fermentation of dietary fibers and production of short-chain fatty acids, which are beneficial for gut health and may influence metabolic processes within the host. Understanding the characteristics and functions of this strain can provide insights into the complex interactions between gut microbiota and human health, emphasizing the importance of maintaining a balanced microbiome for optimal physiological function.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusDorea
SpeciesDorea formicigenerans
Strainstrain AM42-8

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgut
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Dorea formicigenerans strain AM42-8 AM42-8.Scaf41, whole genome

Gene Summary

Adenine Count

1045947 bp

Thymine Count

955694 bp

Guanine Count

733057 bp

Cytosine Count

617338 bp

Genome Length

3352156 bp

Protein-coding Genes

3009 genes

Non-Coding Genes

65 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nif3-like dinuclear metal center hexameric proteinDW924_06585Not AvailablePositive1365812 - 136662429522.0
nucleoside kinaseDW924_06590Not AvailablePositive1366669 - 136833964536.5
extracellular solute-binding proteinDW924_06595Not AvailableNegative1368515 - 137041371550.4
abc transporter permeaseDW924_06600Not AvailableNegative1370410 - 137125531148.4
abc transporter atp-binding proteinDW924_06605Not AvailableNegative1371227 - 137230040060.2
helix-turn-helix domain-containing proteinDW924_06610Not AvailableNegative1372388 - 137292720293.1
amino acid abc transporter substrate-binding proteinDW924_06615Not AvailablePositive1373413 - 137419829334.8
response regulatorDW924_06620Not AvailablePositive1374195 - 1377182113039.0
molybdopterin dehydrogenaseDW924_06625Not AvailablePositive1377298 - 137811030164.8
(2fe-2s)-binding proteinDW924_06630Not AvailablePositive1378100 - 137858517910.7

Displaying genes 1281 – 1290 of 3074 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.