Dorea formicigenerans strain AM42-8

Gram-positiveAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Dorea

Description

Dorea formicigenerans strain AM42-8 is a Gram-positive anaerobic bacterium predominantly found in the gut of Homo sapiens. This strain is characterized by its ability to thrive in an oxygen-free environment, which is typical for microorganisms residing in the human gastrointestinal tract. Additionally, D. formicigenerans possesses flagella, allowing for motility in its natural habitat. The genetic makeup of Dorea formicigenerans strain AM42-8 includes a single replicon, indicating a streamlined genomic organization. This trait may contribute to its adaptability and efficiency in nutrient utilization within the gut ecosystem. The strain is cataloged under the accession number QSFS00000000.1, which provides a reference point for genomic and taxonomic studies. The presence of Dorea formicigenerans within the human gut microbiome highlights its potential role in human health. As an anaerobe, it may contribute to the fermentation of dietary fibers and production of short-chain fatty acids, which are beneficial for gut health and may influence metabolic processes within the host. Understanding the characteristics and functions of this strain can provide insights into the complex interactions between gut microbiota and human health, emphasizing the importance of maintaining a balanced microbiome for optimal physiological function.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusDorea
SpeciesDorea formicigenerans
Strainstrain AM42-8

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgut
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Dorea formicigenerans strain AM42-8 AM42-8.Scaf41, whole genome

Gene Summary

Adenine Count

1045947 bp

Thymine Count

955694 bp

Guanine Count

733057 bp

Cytosine Count

617338 bp

Genome Length

3352156 bp

Protein-coding Genes

3009 genes

Non-Coding Genes

65 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
alanine racemaseDW924_05395Not AvailableNegative1118966 - 112013543651.8
nad(p)h-hydrate dehydrataseDW924_05400Not AvailableNegative1120139 - 112165354868.0
redox-sensing transcriptional repressor rexDW924_05405Not AvailableNegative1121734 - 112237524282.1
abc transporter atp-binding proteinDW924_05410Not AvailablePositive1122579 - 112450472840.8
nudix domain-containing proteinDW924_05415Not AvailableNegative1124519 - 112502219487.7
nadp-dependent isocitrate dehydrogenaseDW924_05420Not AvailableNegative1125038 - 112623745154.8
gntr family transcriptional regulatorDW924_05425Not AvailableNegative1126297 - 112695325238.5
threonine ammonia-lyaseDW924_05430Not AvailableNegative1127244 - 112845843534.7
signal recognition particle-docking protein ftsyDW924_05435Not AvailableNegative1128452 - 112954039979.9
chromosome segregation protein smcDW924_05440Not AvailableNegative1129524 - 1133084135863.0

Displaying genes 1061 – 1070 of 3074 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.