Dorea formicigenerans strain AF12-11

Gram-positiveAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Dorea

Description

Dorea formicigenerans strain AF12-11 is a Gram-positive, anaerobic bacterium primarily inhabiting the gut of Homo sapiens. This strain is characterized by its possession of flagella, which may contribute to its motility within the intestinal environment. Dorea formicigenerans has been identified with a single replicon, indicating a relatively straightforward genomic structure, which can be advantageous for genetic stability and adaptability in its niche. As an anaerobe, Dorea formicigenerans thrives in oxygen-depleted conditions typical of the human gut microbiome. This habitat is crucial for its survival, as the gut provides a rich source of nutrients and a stable environment conducive to the growth of anaerobic microorganisms. The presence of Dorea formicigenerans in the human gut is of particular interest due to its potential roles in digestion and metabolism, as well as its interactions with the host's immune system and other gut microbiota. The accession number for this strain is QSAJ00000000.1, which allows for further exploration and study of its genomic characteristics. Understanding the specific traits and behaviors of Dorea formicigenerans can provide insights into its ecological role within the gut microbiome, as it may contribute to the overall health and functionality of the digestive system in humans.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusDorea
SpeciesDorea formicigenerans
Strainstrain AF12-11

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgut
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Dorea formicigenerans strain AF12-11 AF12-11.Scaf106, whole genome

Gene Summary

Adenine Count

964922 bp

Thymine Count

994732 bp

Guanine Count

647497 bp

Cytosine Count

687759 bp

Genome Length

3295396 bp

Protein-coding Genes

2744 genes

Non-Coding Genes

97 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
yhge/pip domain-containing proteinDWV67_11390Not AvailablePositive2326217 - 232840077565.9
argininosuccinate synthaseDWV67_11405Not AvailablePositive2330973 - 233219945467.6
signal peptidase iiDWV67_11410Not AvailableNegative2332293 - 233275717545.9
peptidaseDWV67_11415Not AvailableNegative2332924 - 233465763861.5
atp-dependent clp protease atp-binding subunit clpxDWV67_11420Not AvailableNegative2334836 - 233626652925.5
hypothetical proteinDWV67_11435Not AvailableNegative2338967 - 234134889587.6
6,7-dimethyl-8-ribityllumazine synthaseDWV67_11445Not AvailableNegative2342372 - 234284516548.3
bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/gtp cyclohydrolase iiDWV67_11450Not AvailableNegative2342877 - 234409445830.9
riboflavin synthaseDWV67_11455Not AvailableNegative2344135 - 234480023775.8
bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase ribdDWV67_11460Not AvailableNegative2344782 - 234590941496.6

Displaying genes 2031 – 2040 of 2841 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.