Dorea formicigenerans strain AF12-11

Gram-positiveAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Dorea

Description

Dorea formicigenerans strain AF12-11 is a Gram-positive, anaerobic bacterium primarily inhabiting the gut of Homo sapiens. This strain is characterized by its possession of flagella, which may contribute to its motility within the intestinal environment. Dorea formicigenerans has been identified with a single replicon, indicating a relatively straightforward genomic structure, which can be advantageous for genetic stability and adaptability in its niche. As an anaerobe, Dorea formicigenerans thrives in oxygen-depleted conditions typical of the human gut microbiome. This habitat is crucial for its survival, as the gut provides a rich source of nutrients and a stable environment conducive to the growth of anaerobic microorganisms. The presence of Dorea formicigenerans in the human gut is of particular interest due to its potential roles in digestion and metabolism, as well as its interactions with the host's immune system and other gut microbiota. The accession number for this strain is QSAJ00000000.1, which allows for further exploration and study of its genomic characteristics. Understanding the specific traits and behaviors of Dorea formicigenerans can provide insights into its ecological role within the gut microbiome, as it may contribute to the overall health and functionality of the digestive system in humans.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusDorea
SpeciesDorea formicigenerans
Strainstrain AF12-11

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgut
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Dorea formicigenerans strain AF12-11 AF12-11.Scaf106, whole genome

Gene Summary

Adenine Count

964922 bp

Thymine Count

994732 bp

Guanine Count

647497 bp

Cytosine Count

687759 bp

Genome Length

3295396 bp

Protein-coding Genes

2744 genes

Non-Coding Genes

97 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
rna polymerase sporulation sigma factor sigeDWV67_05520Not AvailablePositive1132230 - 113297027902.0
mbl fold metallo-hydrolaseDWV67_05525Not AvailablePositive1133008 - 113461559526.2
rna polymerase sporulation sigma factor siggDWV67_05530Not AvailablePositive1134809 - 113558829719.7
is4/is5 family transposaseDWV67_05535Not AvailablePositive1135830 - 11359655264.48
xre family transcriptional regulatorDWV67_05540Not AvailableNegative1136293 - 113661011497.0
response regulatorDWV67_05545Not AvailableNegative1136936 - 1139764106210.0
response regulatorDWV67_05550Not AvailableNegative1140115 - 1142928106161.0
amino acid abc transporter substrate-binding proteinDWV67_05560Not AvailableNegative1145300 - 114611530475.4
response regulatorDWV67_05565Not AvailableNegative1146175 - 114832880419.2
carbohydrate abc transporter substrate-binding proteinDWV67_05570Not AvailableNegative1148475 - 115031969741.8

Displaying genes 1011 – 1020 of 2841 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.