Dorea formicigenerans strain AF25-11

Gram-positiveAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Dorea

Description

Dorea formicigenerans strain AF25-11 is a Gram-positive anaerobic bacterium predominantly found in the gut of Homo sapiens. This strain is characterized by its ability to thrive in oxygen-free environments, which is typical for many gut microbiota. The presence of flagella suggests that Dorea formicigenerans can exhibit motility, potentially aiding its colonization and interaction within the gut ecosystem. Dorea formicigenerans strain AF25-11 is notable for having a single replicon, indicating a streamlined genetic organization that may contribute to its adaptability in the complex gut environment. The accession number QRUK00000000.1 provides a reference for further genomic studies and sequence data related to this strain. Understanding the ecological role of Dorea formicigenerans in the human gut is crucial, as members of the Dorea genus are often involved in fermentation processes and the breakdown of complex carbohydrates. This metabolic activity can influence the microbial community structure and the overall health of the host. The ability of Dorea formicigenerans to survive and function in the anaerobic conditions of the gut underscores its potential significance in maintaining gut homeostasis and contributing to the host's metabolic profile.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusDorea
SpeciesDorea formicigenerans
Strainstrain AF25-11

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgut
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Dorea formicigenerans strain AF25-11 AF25-11.Scaf102, whole genome

Gene Summary

Adenine Count

980208 bp

Thymine Count

977970 bp

Guanine Count

671148 bp

Cytosine Count

672805 bp

Genome Length

3302668 bp

Protein-coding Genes

3025 genes

Non-Coding Genes

89 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
gntr family transcriptional regulatorDWY33_03235Not AvailablePositive690418 - 69107425238.5
nadp-dependent isocitrate dehydrogenaseDWY33_03240Not AvailablePositive691134 - 69233345154.8
nudix domain-containing proteinDWY33_03245Not AvailablePositive692349 - 69285219459.7
abc transporter atp-binding proteinDWY33_03250Not AvailableNegative692867 - 69479272859.9
redox-sensing transcriptional repressor rexDWY33_03255Not AvailablePositive694996 - 69563724282.1
nad(p)h-hydrate dehydrataseDWY33_03260Not AvailablePositive695718 - 69723254868.0
alanine racemaseDWY33_03265Not AvailablePositive697236 - 69840543649.9
type ii toxin-antitoxin system pemk/mazf family toxinDWY33_03270Not AvailablePositive698542 - 69888913120.1
hlyc/corc family transporterDWY33_03275Not AvailablePositive698916 - 69965328671.5
yebc/pmpr family dna-binding transcriptional regulatorDWY33_03280Not AvailablePositive699698 - 70042926623.8

Displaying genes 691 – 700 of 3114 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.