Dorea formicigenerans strain AF25-11

Gram-positiveAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Dorea

Description

Dorea formicigenerans strain AF25-11 is a Gram-positive anaerobic bacterium predominantly found in the gut of Homo sapiens. This strain is characterized by its ability to thrive in oxygen-free environments, which is typical for many gut microbiota. The presence of flagella suggests that Dorea formicigenerans can exhibit motility, potentially aiding its colonization and interaction within the gut ecosystem. Dorea formicigenerans strain AF25-11 is notable for having a single replicon, indicating a streamlined genetic organization that may contribute to its adaptability in the complex gut environment. The accession number QRUK00000000.1 provides a reference for further genomic studies and sequence data related to this strain. Understanding the ecological role of Dorea formicigenerans in the human gut is crucial, as members of the Dorea genus are often involved in fermentation processes and the breakdown of complex carbohydrates. This metabolic activity can influence the microbial community structure and the overall health of the host. The ability of Dorea formicigenerans to survive and function in the anaerobic conditions of the gut underscores its potential significance in maintaining gut homeostasis and contributing to the host's metabolic profile.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusDorea
SpeciesDorea formicigenerans
Strainstrain AF25-11

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatgut
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Dorea formicigenerans strain AF25-11 AF25-11.Scaf102, whole genome

Gene Summary

Adenine Count

980208 bp

Thymine Count

977970 bp

Guanine Count

671148 bp

Cytosine Count

672805 bp

Genome Length

3302668 bp

Protein-coding Genes

3025 genes

Non-Coding Genes

89 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
pyridoxal phosphate-dependent aminotransferaseDWY33_00155Not AvailablePositive35437 - 3662443942.4
histidinol-phosphate transaminaseDWY33_00160Not AvailablePositive36677 - 3773540771.4
small multi-drug export proteinDWY33_00165Not AvailablePositive37787 - 3829918218.6
3-deoxy-7-phosphoheptulonate synthaseDWY33_00170Not AvailablePositive38348 - 3937938920.6
xre family transcriptional regulatorDWY33_00175Not AvailableNegative39411 - 3976413397.0
hypothetical proteinDWY33_00180Not AvailablePositive40064 - 4052517279.4
flavodoxin-dependent (e)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthaseDWY33_00185Not AvailablePositive40609 - 4166437584.1
polc-type dna polymerase iiiDWY33_00190Not AvailablePositive41657 - 46222171409.0
anaerobic ribonucleoside-triphosphate reductaseDWY33_00195Not AvailablePositive46462 - 4865183257.9
anaerobic ribonucleoside-triphosphate reductase activating proteinDWY33_00200Not AvailablePositive48770 - 4926418932.7

Displaying genes 91 – 100 of 3114 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.