Mediterraneibacter gnavus strain AM25-19

Gram-positiveCocciNon-motileAnaerobic

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Mediterraneibacter

Description

Mediterraneibacter gnavus strain AM25-19 is a Gram-positive, non-motile coccus that thrives in anaerobic environments, specifically within the intestinal microflora of Homo sapiens. This strain is classified as a chemoheterotroph, indicating that it derives energy through the consumption of organic compounds. It exhibits mesophilic characteristics, with an optimal growth temperature of 37°C, which is consistent with the average internal temperature of the human body. Notably, M. gnavus strain AM25-19 has been associated with human health, particularly in relation to inflammatory bowel disease (IBD). Its pathogenicity suggests a potential role in the etiology or exacerbation of this condition, although the precise mechanisms remain to be elucidated. The strain does not form spores, which may influence its survival and replication strategies within the gut environment. With a single replicon, M. gnavus strain AM25-19 may have a simplified genomic architecture that could affect its adaptability and interactions within the host's intestinal ecosystem. The strain's presence in the human gut microbiome highlights its potential significance in gastrointestinal health and disease, emphasizing the complex interplay between gut microbiota and host health. Further research may provide insights into the specific contributions of this strain to IBD and overall gut health.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusMediterraneibacter
SpeciesMediterraneibacter gnavus
Strainstrain AM25-19

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Mediterraneibacter gnavus strain AM25-19
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatAnimal intestinal microflora
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Mediterraneibacter gnavus strain AM25-19 AM25-19.Scaf63, whole

Gene Summary

Adenine Count

861174 bp

Thymine Count

817053 bp

Guanine Count

669659 bp

Cytosine Count

598562 bp

Genome Length

2946548 bp

Protein-coding Genes

2656 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
alanine racemaseDW671_01695Not AvailablePositive372563 - 37371142983.7
type ii toxin-antitoxin system pemk/mazf family toxinDW671_01700Not AvailablePositive373809 - 37415612933.9
yebc/pmpr family dna-binding transcriptional regulatorDW671_01705Not AvailablePositive374256 - 37498726766.2
hypothetical proteinDW671_01710Not AvailablePositive375355 - 37613429949.0
o-acetylhomoserine aminocarboxypropyltransferase/cysteine synthaseDW671_01715Not AvailablePositive376127 - 37740146642.4
clp proteaseDW671_01720Not AvailablePositive377555 - 37824425013.2
dna translocase ftskDW671_01725Not AvailablePositive378309 - 38087392959.6
formate--tetrahydrofolate ligaseDW671_01730Not AvailablePositive380893 - 38256360330.0
bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase foldDW671_01735Not AvailablePositive382575 - 38341430393.0
endoglucanaseDW671_01740Not AvailablePositive383426 - 38466746665.3

Displaying genes 331 – 340 of 2716 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Inflammatory bowel disease (ibd)CausesPMC12034673

Displaying health effects 1 – 1 of 1 in total