Mediterraneibacter gnavus strain AM25-19

Gram-positiveCocciNon-motileAnaerobic

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Lachnospirales

Family

Lachnospiraceae

Genus

Mediterraneibacter

Description

Mediterraneibacter gnavus strain AM25-19 is a Gram-positive, non-motile coccus that thrives in anaerobic environments, specifically within the intestinal microflora of Homo sapiens. This strain is classified as a chemoheterotroph, indicating that it derives energy through the consumption of organic compounds. It exhibits mesophilic characteristics, with an optimal growth temperature of 37°C, which is consistent with the average internal temperature of the human body. Notably, M. gnavus strain AM25-19 has been associated with human health, particularly in relation to inflammatory bowel disease (IBD). Its pathogenicity suggests a potential role in the etiology or exacerbation of this condition, although the precise mechanisms remain to be elucidated. The strain does not form spores, which may influence its survival and replication strategies within the gut environment. With a single replicon, M. gnavus strain AM25-19 may have a simplified genomic architecture that could affect its adaptability and interactions within the host's intestinal ecosystem. The strain's presence in the human gut microbiome highlights its potential significance in gastrointestinal health and disease, emphasizing the complex interplay between gut microbiota and host health. Further research may provide insights into the specific contributions of this strain to IBD and overall gut health.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderLachnospirales
FamilyLachnospiraceae
GenusMediterraneibacter
SpeciesMediterraneibacter gnavus
Strainstrain AM25-19

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Mediterraneibacter gnavus strain AM25-19
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatAnimal intestinal microflora
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Mediterraneibacter gnavus strain AM25-19 AM25-19.Scaf63, whole

Gene Summary

Adenine Count

861174 bp

Thymine Count

817053 bp

Guanine Count

669659 bp

Cytosine Count

598562 bp

Genome Length

2946548 bp

Protein-coding Genes

2656 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
d-alanyl-d-alanine carboxypeptidaseDW671_08355Not AvailablePositive1742353 - 174362447393.7
2-isopropylmalate synthaseDW671_08360Not AvailablePositive1743738 - 174572675633.2
carboxyl transferaseDW671_08365Not AvailablePositive1745917 - 174735350910.4
duf3887 domain-containing proteinDW671_08370Not AvailablePositive1747368 - 174814728390.6
acetyl-coa carboxylase biotin carboxyl carrier protein subunitDW671_08375Not AvailablePositive1748164 - 174853211815.1
sodium ion-translocating decarboxylase subunit betaDW671_08380Not AvailablePositive1748546 - 174969740380.7
oxaloacetate decarboxylase subunit alphaDW671_08385Not AvailablePositive1749716 - 175113152610.9
m24 family metallopeptidaseDW671_08390Not AvailablePositive1751268 - 175305868232.6
murr/rpir family transcriptional regulatorDW671_08395Not AvailablePositive1753133 - 175403533639.5
nad(p)/fad-dependent oxidoreductaseDW671_08400Not AvailablePositive1754028 - 175525745381.9

Displaying genes 1621 – 1630 of 2716 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Inflammatory bowel disease (ibd)CausesPMC12034673

Displaying health effects 1 – 1 of 1 in total