Enterococcus faecalis strain 10-2-12

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Enterococcaceae

Genus

Enterococcus

Description

Enterococcus faecalis strain 10-2-12 is a Gram-positive, non-motile cocci bacterium classified as a facultative anaerobe. It thrives as a chemoorganotroph, utilizing organic compounds for energy. This strain is mesophilic, with an optimal growth temperature of 37°C, and possesses a single membrane and a single replicon. E. faecalis strain 10-2-12 is free-living, with a diverse range of hosts that includes Homo sapiens, Gallus gallus, Bos, various Metazoa, Lutjanus russellii, Danio rerio, Sus scrofa, Insecta, Canis lupus familiaris, Felis catus, and Phocoena phocoena. Its presence in these varied organisms indicates its ecological versatility and adaptability. This strain is associated with a broad spectrum of health effects, particularly in humans, where it is known to cause infections such as bacteremia, urinary tract infections (UTIs), endocarditis, and meningitis, among others. It is notable for its role in nosocomial infections and other complications, including intestinal inflammation and septicemia. The capacity of E. faecalis to cause infections across multiple anatomical sites, including surgical sites and the oral cavity, underscores its pathogenic potential. The presence of E. faecalis strain 10-2-12 in both human and animal hosts suggests a significant ecological role, potentially acting as a commensal organism in healthy individuals but becoming pathogenic under certain conditions. This duality highlights the importance of understanding the environmental and biological factors that govern its pathogenicity and the implications for health care and veterinary medicine.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyEnterococcaceae
GenusEnterococcus
SpeciesEnterococcus faecalis
Strainstrain 10-2-12

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Enterococcus faecalis strain 10-2-12
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos
Cell arrangementChains
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Enterococcus faecalis strain 10-2-12

Gene Summary

Adenine Count

867754 bp

Thymine Count

886141 bp

Guanine Count

517148 bp

Cytosine Count

537949 bp

Genome Length

2809172 bp

Protein-coding Genes

2647 genes

Non-Coding Genes

167 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphate starvation-inducible protein phohDV494_01135Not AvailableNegative254983 - 25595735905.7
gatb/yqey domain-containing proteinDV494_01140Not AvailableNegative256140 - 25658916753.4
30s ribosomal protein s21DV494_01145Not AvailableNegative256615 - 2567916930.46
transcriptional repressorDV494_01150Not AvailableNegative256957 - 25739117146.7
kinase/pyrophosphorylaseDV494_01155Not AvailablePositive257523 - 25835330979.2
homoserine kinaseDV494_01160Not AvailableNegative258398 - 25926131435.1
threonine synthaseDV494_01165Not AvailableNegative259258 - 26031337164.7
homoserine dehydrogenaseDV494_01170Not AvailableNegative260316 - 26160846733.3
arsr family transcriptional regulatorDV494_01175Not AvailableNegative261661 - 26194811175.6
pyrroline-5-carboxylate reductaseDV494_01180Not AvailableNegative262086 - 26286827404.4

Displaying genes 361 – 370 of 2814 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
EndophthalmitisCausesPMC10638747
Refractory apical periodontitisCausesPMC11307051
Infections in various body parts such as urinary tract, intra-abdomen and pelvic regions, surgical sites and oral cavityCausesPMC11307051
EndocarditisCausesPMC11784074
Bloodstream infectionsCausesPMC11784074
Urinary tract infectionsCausesPMC11784074
MastitisCausesPMC13343983
PyelonephritisCausesPMC4308012
Various infectionsCausesPMC5109407
MeningitisCausesPMC5109407

Displaying health effects 1 – 10 of 47 in total