Enterococcus faecalis strain 10-2-12

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Enterococcaceae

Genus

Enterococcus

Description

Enterococcus faecalis strain 10-2-12 is a Gram-positive, non-motile cocci bacterium classified as a facultative anaerobe. It thrives as a chemoorganotroph, utilizing organic compounds for energy. This strain is mesophilic, with an optimal growth temperature of 37°C, and possesses a single membrane and a single replicon. E. faecalis strain 10-2-12 is free-living, with a diverse range of hosts that includes Homo sapiens, Gallus gallus, Bos, various Metazoa, Lutjanus russellii, Danio rerio, Sus scrofa, Insecta, Canis lupus familiaris, Felis catus, and Phocoena phocoena. Its presence in these varied organisms indicates its ecological versatility and adaptability. This strain is associated with a broad spectrum of health effects, particularly in humans, where it is known to cause infections such as bacteremia, urinary tract infections (UTIs), endocarditis, and meningitis, among others. It is notable for its role in nosocomial infections and other complications, including intestinal inflammation and septicemia. The capacity of E. faecalis to cause infections across multiple anatomical sites, including surgical sites and the oral cavity, underscores its pathogenic potential. The presence of E. faecalis strain 10-2-12 in both human and animal hosts suggests a significant ecological role, potentially acting as a commensal organism in healthy individuals but becoming pathogenic under certain conditions. This duality highlights the importance of understanding the environmental and biological factors that govern its pathogenicity and the implications for health care and veterinary medicine.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyEnterococcaceae
GenusEnterococcus
SpeciesEnterococcus faecalis
Strainstrain 10-2-12

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Enterococcus faecalis strain 10-2-12
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos
Cell arrangementChains
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Enterococcus faecalis strain 10-2-12

Gene Summary

Adenine Count

867754 bp

Thymine Count

886141 bp

Guanine Count

517148 bp

Cytosine Count

537949 bp

Genome Length

2809172 bp

Protein-coding Genes

2647 genes

Non-Coding Genes

167 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
serine hydroxymethyltransferaseDV494_05595Not AvailableNegative1166048 - 116728644540.9
threonylcarbamoyl-amp synthaseDV494_05600Not AvailableNegative1167362 - 116838436591.4
peptide chain release factor n(5)-glutamine methyltransferaseDV494_05605Not AvailableNegative1168428 - 116926131286.2
peptide chain release factor 1DV494_05610Not AvailableNegative1169254 - 117032740249.6
thymidine kinaseDV494_05615Not AvailableNegative1170339 - 117092322467.0
flavocytochrome cDV494_05620Not AvailableNegative1171150 - 117266753817.8
trkh family potassium uptake proteinDV494_05625Not AvailablePositive1173037 - 117445253475.8
pyruvate:ferredoxin (flavodoxin) oxidoreductaseDV494_05630Not AvailableNegative1174488 - 1178021130523.0
nadph-dependent glutamate synthaseDV494_05635Not AvailableNegative1178042 - 117946050889.4
sulfide/dihydroorotate dehydrogenase-like fad/nad-binding proteinDV494_05640Not AvailableNegative1179453 - 118029230575.2

Displaying genes 1241 – 1250 of 2814 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
EndophthalmitisCausesPMC10638747
Refractory apical periodontitisCausesPMC11307051
Infections in various body parts such as urinary tract, intra-abdomen and pelvic regions, surgical sites and oral cavityCausesPMC11307051
EndocarditisCausesPMC11784074
Bloodstream infectionsCausesPMC11784074
Urinary tract infectionsCausesPMC11784074
MastitisCausesPMC13343983
PyelonephritisCausesPMC4308012
Various infectionsCausesPMC5109407
MeningitisCausesPMC5109407

Displaying health effects 1 – 10 of 47 in total