Enterococcus faecalis strain 12-1VP

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Enterococcaceae

Genus

Enterococcus

Description

Enterococcus faecalis strain 12-1VP is a Gram-positive, non-motile cocci bacterium classified as a chemoorganotroph. This strain is facultative anaerobic, meaning it can survive in both the presence and absence of oxygen, with an optimal growth temperature of 37°C, placing it in the mesophilic temperature range. It possesses a single membrane and a single replicon. This bacterium is free-living and has a diverse array of known hosts, including Homo sapiens, various livestock species (Bos, Sus scrofa), birds (Gallus gallus), aquatic species (Lutjanus russellii, Danio rerio), and several types of mammals (Canis lupus familiaris, Felis catus, Phocoena phocoena), as well as insects (Insecta). E. faecalis strain 12-1VP is associated with numerous health impacts in humans, contributing to conditions such as bacteremia, urinary tract infections (UTIs), endocarditis, meningitis, and various nosocomial infections. It is known to cause infections in different body parts, including the urinary tract, abdomen, and surgical sites. Particularly concerning is its role in catheter-associated urinary tract infections (CAUTI) and its contribution to neonatal infections, indicating its significant pathogenicity in human health. The strain's ability to thrive in a variety of environments and its pathogenic potential underlines its ecological adaptability. Its presence in both human and animal hosts highlights the importance of monitoring E. faecalis in clinical settings, given its association with serious infections and the potential for transmission between species.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyEnterococcaceae
GenusEnterococcus
SpeciesEnterococcus faecalis
Strainstrain 12-1VP

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Enterococcus faecalis strain 12-1VP
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos
Cell arrangementChains
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Enterococcus faecalis strain 12-1VP

Gene Summary

Adenine Count

854535 bp

Thymine Count

884035 bp

Guanine Count

507360 bp

Cytosine Count

539632 bp

Genome Length

2785742 bp

Protein-coding Genes

2631 genes

Non-Coding Genes

168 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
peptide chain release factor 1DV498_06275Not AvailableNegative1280216 - 128128940249.6
thymidine kinaseDV498_06280Not AvailableNegative1281301 - 128188522467.0
flavocytochrome cDV498_06285Not AvailableNegative1282112 - 128362953817.8
trkh family potassium uptake proteinDV498_06290Not AvailablePositive1283999 - 128541453475.8
pyruvate:ferredoxin (flavodoxin) oxidoreductaseDV498_06295Not AvailableNegative1285450 - 1288983130523.0
nadph-dependent glutamate synthaseDV498_06300Not AvailableNegative1289004 - 129042250889.4
sulfide/dihydroorotate dehydrogenase-like fad/nad-binding proteinDV498_06305Not AvailableNegative1290415 - 129125430575.2
flavodoxinDV498_06310Not AvailableNegative1291310 - 129176816809.3
ef2563 family selenium-dependent molybdenum hydroxylase system proteinDV498_06315Not AvailableNegative1292010 - 129280428620.3
putative selenium-dependent hydroxylase accessory protein yqecDV498_06320Not AvailableNegative1292804 - 129355928368.9

Displaying genes 1371 – 1380 of 2799 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
EndophthalmitisCausesPMC10638747
Refractory apical periodontitisCausesPMC11307051
Infections in various body parts such as urinary tract, intra-abdomen and pelvic regions, surgical sites and oral cavityCausesPMC11307051
EndocarditisCausesPMC11784074
Bloodstream infectionsCausesPMC11784074
Urinary tract infectionsCausesPMC11784074
MastitisCausesPMC13343983
PyelonephritisCausesPMC4308012
Various infectionsCausesPMC5109407
MeningitisCausesPMC5109407

Displaying health effects 1 – 10 of 47 in total