Enterococcus faecalis strain 5A-2

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Enterococcaceae

Genus

Enterococcus

Description

Enterococcus faecalis strain 5A-2 is a Gram-positive, cocci-shaped bacterium that operates as a chemoorganotroph, utilizing organic compounds for energy. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It has a mesophilic growth range, with an optimal temperature of 37°C. Notably, Enterococcus faecalis 5A-2 is non-motile and possesses a single membrane, along with one replicon. This strain demonstrates a free-living biotic relationship and has been isolated from multiple habitats. It has a wide host range, infecting various organisms, including humans (Homo sapiens), domestic animals such as chickens (Gallus gallus), cattle (Bos), and other metazoans, as well as aquatic species like Lutjanus russellii and Danio rerio. Enterococcus faecalis 5A-2 is associated with numerous health complications, particularly in humans. It is known to cause bacteremia, urinary tract infections (UTIs), endocarditis, meningitis, and various nosocomial infections. The strain is implicated in infections across different body regions, including the urinary tract, intra-abdomen, and surgical sites, as well as complications such as septicemia and dental abscesses. The ecological insight drawn from the pathogenicity of Enterococcus faecalis strain 5A-2 emphasizes its role as a significant opportunistic pathogen in humans and other animals. Its capacity to thrive in diverse environments and infect multiple hosts highlights the importance of monitoring its presence in clinical settings and understanding its transmission dynamics to mitigate associated health risks.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyEnterococcaceae
GenusEnterococcus
SpeciesEnterococcus faecalis
Strainstrain 5A-2

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Enterococcus faecalis strain 5A-2
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos
Cell arrangementChains
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Enterococcus faecalis strain 5A-2

Gene Summary

Adenine Count

872276 bp

Thymine Count

881528 bp

Guanine Count

522772 bp

Cytosine Count

532520 bp

Genome Length

2809276 bp

Protein-coding Genes

2657 genes

Non-Coding Genes

170 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
enolaseDVY34_00375Not AvailableNegative77140 - 7843846514.1
triose-phosphate isomeraseDVY34_00380Not AvailableNegative78570 - 7932526901.8
phosphoglycerate kinaseDVY34_00385Not AvailableNegative79374 - 8056742369.7
type i glyceraldehyde-3-phosphate dehydrogenaseDVY34_00390Not AvailableNegative80694 - 8169535773.6
sorc family transcriptional regulatorDVY34_00395Not AvailableNegative81735 - 8277238460.1
yitt family proteinDVY34_00400Not AvailableNegative83192 - 8407032538.2
tigr01440 family proteinDVY34_00405Not AvailableNegative84213 - 8478220502.7
ecf transporter s componentDVY34_00410Not AvailableNegative84779 - 8529718421.2
bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinaseDVY34_00415Not AvailableNegative85269 - 8608429269.4
aspartate--trna ligaseDVY34_00420Not AvailableNegative86255 - 8802466574.4

Displaying genes 211 – 220 of 2827 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
EndophthalmitisCausesPMC10638747
Refractory apical periodontitisCausesPMC11307051
Infections in various body parts such as urinary tract, intra-abdomen and pelvic regions, surgical sites and oral cavityCausesPMC11307051
EndocarditisCausesPMC11784074
Bloodstream infectionsCausesPMC11784074
Urinary tract infectionsCausesPMC11784074
MastitisCausesPMC13343983
PyelonephritisCausesPMC4308012
Various infectionsCausesPMC5109407
MeningitisCausesPMC5109407

Displaying health effects 1 – 10 of 47 in total