Enterococcus faecalis strain 5A-2

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Enterococcaceae

Genus

Enterococcus

Description

Enterococcus faecalis strain 5A-2 is a Gram-positive, cocci-shaped bacterium that operates as a chemoorganotroph, utilizing organic compounds for energy. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It has a mesophilic growth range, with an optimal temperature of 37°C. Notably, Enterococcus faecalis 5A-2 is non-motile and possesses a single membrane, along with one replicon. This strain demonstrates a free-living biotic relationship and has been isolated from multiple habitats. It has a wide host range, infecting various organisms, including humans (Homo sapiens), domestic animals such as chickens (Gallus gallus), cattle (Bos), and other metazoans, as well as aquatic species like Lutjanus russellii and Danio rerio. Enterococcus faecalis 5A-2 is associated with numerous health complications, particularly in humans. It is known to cause bacteremia, urinary tract infections (UTIs), endocarditis, meningitis, and various nosocomial infections. The strain is implicated in infections across different body regions, including the urinary tract, intra-abdomen, and surgical sites, as well as complications such as septicemia and dental abscesses. The ecological insight drawn from the pathogenicity of Enterococcus faecalis strain 5A-2 emphasizes its role as a significant opportunistic pathogen in humans and other animals. Its capacity to thrive in diverse environments and infect multiple hosts highlights the importance of monitoring its presence in clinical settings and understanding its transmission dynamics to mitigate associated health risks.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyEnterococcaceae
GenusEnterococcus
SpeciesEnterococcus faecalis
Strainstrain 5A-2

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Enterococcus faecalis strain 5A-2
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos
Cell arrangementChains
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Enterococcus faecalis strain 5A-2

Gene Summary

Adenine Count

872276 bp

Thymine Count

881528 bp

Guanine Count

522772 bp

Cytosine Count

532520 bp

Genome Length

2809276 bp

Protein-coding Genes

2657 genes

Non-Coding Genes

170 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
peptide chain release factor n(5)-glutamine methyltransferaseDVY34_07675Not AvailableNegative1576233 - 157706631286.2
peptide chain release factor 1DVY34_07680Not AvailableNegative1577059 - 157813240249.6
thymidine kinaseDVY34_07685Not AvailableNegative1578144 - 157872822467.0
flavocytochrome cDVY34_07690Not AvailableNegative1578955 - 158047253817.8
trkh family potassium uptake proteinDVY34_07695Not AvailablePositive1580842 - 158225753475.8
pyruvate:ferredoxin (flavodoxin) oxidoreductaseDVY34_07700Not AvailableNegative1582293 - 1585826130523.0
nadph-dependent glutamate synthaseDVY34_07705Not AvailableNegative1585847 - 158726550889.4
sulfide/dihydroorotate dehydrogenase-like fad/nad-binding proteinDVY34_07710Not AvailableNegative1587258 - 158809730575.2
flavodoxinDVY34_07715Not AvailableNegative1588153 - 158861116809.3
ef2563 family selenium-dependent molybdenum hydroxylase system proteinDVY34_07720Not AvailableNegative1588853 - 158964728620.3

Displaying genes 1651 – 1660 of 2827 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
EndophthalmitisCausesPMC10638747
Refractory apical periodontitisCausesPMC11307051
Infections in various body parts such as urinary tract, intra-abdomen and pelvic regions, surgical sites and oral cavityCausesPMC11307051
EndocarditisCausesPMC11784074
Bloodstream infectionsCausesPMC11784074
Urinary tract infectionsCausesPMC11784074
MastitisCausesPMC13343983
PyelonephritisCausesPMC4308012
Various infectionsCausesPMC5109407
MeningitisCausesPMC5109407

Displaying health effects 1 – 10 of 47 in total