Escherichia coli strain AVC154

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain AVC154 is a Gram-negative, rod-shaped bacterium that thrives as a facultative anaerobe, making it adaptable to environments with varying oxygen levels. It exhibits mobility due to the presence of flagella and typically arranges itself in pairs or singles. The optimal temperature for its growth is 37°C, placing it within the mesophilic temperature range. This strain is host-associated and has a diverse range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and several other vertebrates and invertebrates. Its biotic relationship is characterized as free-living, suggesting that while it can dwell within hosts, it also exists independently in the environment. E. coli AVC154 is associated with numerous health effects, particularly in humans, where it is linked to urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as neonatal meningitis and hemolytic uremic syndrome (HUS). The strain's pathogenicity underscores its role as a significant human pathogen, contributing to a range of serious health issues including peritonitis, diarrhea, and even colorectal cancer. The broad host range and diverse pathogenic effects of E. coli strain AVC154 indicate its ecological versatility and potential impact on both human health and animal husbandry. Its ability to thrive in various biological niches emphasizes the importance of monitoring and understanding its behavior in both clinical and environmental contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain AVC154

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain AVC154
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain AVC154 scaffold_229, whole genome shotgun

Gene Summary

Adenine Count

1373421 bp

Thymine Count

1371542 bp

Guanine Count

1390224 bp

Cytosine Count

1384564 bp

Genome Length

5520112 bp

Protein-coding Genes

5254 genes

Non-Coding Genes

451 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
thiamine phosphate synthaseDTM10_25830Not AvailablePositive4905994 - 490662923059.8
thiazole biosynthesis adenylyltransferase thifDTM10_25835Not AvailablePositive4906622 - 490737726952.3
sulfur carrier protein thisDTM10_25840Not AvailablePositive4907361 - 49075617323.77
thiazole synthaseDTM10_25845Not AvailablePositive4907563 - 490833326871.6
2-iminoacetate synthase thihDTM10_25850Not AvailablePositive4908330 - 490946343303.6
dna-directed rna polymerase subunit beta'DTM10_25855Not AvailableNegative4909703 - 4913926155169.0
dna-directed rna polymerase subunit betaDTM10_25860Not AvailableNegative4914003 - 4918031150641.0
50s ribosomal protein l7/l12DTM10_25865Not AvailableNegative4918351 - 491871612295.8
50s ribosomal protein l10DTM10_25870Not AvailableNegative4918783 - 491928017712.6
50s ribosomal protein l1DTM10_25880Not AvailableNegative4919693 - 492039724731.1

Displaying genes 5041 – 5050 of 5705 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total