Enterobacter cloacae strain 99B3

Enterobacter cloacae strain 99B3 is a Gram-negative, facultative anaerobic rod-shaped bacterium. It is a mesophilic organism, indicating that it thrives in moderate temperature ranges. This strain is characterized by its presence of flagella, although it exhibits no mobility. The bacterium has a single replicon and features a double membrane structure typical of Gram-negative bacteria. E. cloacae strain 99B3 is a free-living organism, found in multiple habitats. It has been associated with various health effects in humans, including vertebral osteomyelitis, bacteremia, spondylodiscitis, and both urinary and respiratory tract infections. The strain is particularly notable for its role in bloodstream infections (BSI), which can pose serious health risks. This strain has been documented in relation to several hosts, including Homo sapiens (humans), Bos (cattle), and Okapia johnstoni (okapi). The pathogenicity of E. cloacae strain 99B3 towards humans underscores its potential as an opportunistic pathogen, especially in immunocompromised individuals. In summary, the presence of E. cloacae strain 99B3 in diverse environments and its association with significant health impacts in multiple vertebrate hosts highlight its ecological versatility and importance. Understanding the ecological roles and pathogenic potential of such strains is crucial for addressing infections they may cause in humans and other animals.