Enterobacter cloacae strain GEO_23_Down_A

Gram-negativeRodNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Enterobacter

Description

Enterobacter cloacae strain GEO_23_Down_A is a Gram-negative bacterium characterized by its rod shape and the presence of flagella, which indicates motility despite the reported lack of mobility. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It requires a mesophilic temperature range for optimal growth, making it well-suited for various habitats. The strain has a unique genetic makeup, with one replicon and a structure composed of two membranes, common among Gram-negative bacteria. Enterobacter cloacae is known to have a free-living biotic relationship, indicating its ability to exist independently in various environments. This strain has notable health implications, particularly in humans, where it is associated with a range of infections, including vertebral osteomyelitis, bacteremia, spondylodiscitis, and urinary and respiratory tract infections. These infections can lead to serious conditions such as bloodstream infections (BSIs), highlighting the strain's pathogenicity. GEO_23_Down_A has also been identified in association with other hosts, including Bos and Okapia johnstoni, suggesting its potential ecological versatility. The presence of this strain in diverse habitats and its pathogenic potential in multiple hosts underline the importance of monitoring Enterobacter cloacae in clinical and environmental contexts, as it may pose significant health risks to both humans and animals. Understanding its distribution and behavior in various environments can provide insights into its role in microbial ecosystems and its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEnterobacter
SpeciesEnterobacter cloacae
Strainstrain GEO_23_Down_A

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Enterobacter cloacae strain GEO_23_Down_A
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Bos, Okapia johnstoni
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Enterobacter cloacae strain GEO_23_Down_A

Gene Summary

Adenine Count

1166616 bp

Thymine Count

1171458 bp

Guanine Count

1411149 bp

Cytosine Count

1423346 bp

Genome Length

5173278 bp

Protein-coding Genes

4984 genes

Non-Coding Genes

310 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
marr family transcriptional regulatorDN595_11005Not AvailablePositive2202948 - 220341817912.9
hlyd family secretion proteinDN595_11010Not AvailablePositive2203415 - 220448239635.9
1,4-alpha-glucan branching proteinDN595_11015Not AvailablePositive2204472 - 220554839920.1
duf445 domain-containing proteinDN595_11020Not AvailableNegative2205545 - 220681647970.3
duf2778 domain-containing proteinDN595_11025Not AvailablePositive2207064 - 220742613137.5
hypothetical proteinDN595_11030Not AvailablePositive2207426 - 220793818587.4
type vi secretion system tube protein hcpDN595_11035Not AvailablePositive2207939 - 220843018860.6
lyse family translocatorDN595_11040Not AvailableNegative2208452 - 220907823016.1
arac family transcriptional regulatorDN595_11045Not AvailableNegative2209127 - 220987027511.7
nad-dependent succinate-semialdehyde dehydrogenaseDN595_11050Not AvailablePositive2210020 - 221139049822.2

Displaying genes 2341 – 2350 of 5294 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Vertebral osteomyelitisCausesPMC1004780
BacteremiaCausesPMC1004780
SpondylodiscitisCausesPMC1004780
Bloodstream infectionsCausesPMC10545569
Bloodstream infectionCausesPMC10545569
BsiCausesPMC10545569
Urinary and respiratory tract infectionsCausesPMC8956555

Displaying health effects 1 – 7 of 7 in total