Cutibacterium acnes strain T27324

Cutibacterium acnes strain T27324 is a Gram-positive anaerobic bacterium that is rod-shaped and non-motile. This strain is classified as mesophilic, with an optimal growth temperature of 37°C, which aligns with the average human body temperature, indicating its adaptation to a host-associated habitat primarily within humans (Homo sapiens). The organism has one membrane and a single replicon, which is typical for many bacteria in its classification. Cutibacterium acnes is known for its diverse biotic relationships, functioning as a free-living bacterium. However, it is also linked to various health issues, including acute bacterial meningitis, thoracic actinomycosis, and common acne. Additionally, it has been associated with more severe conditions such as epithelial ovarian cancer and infectious complications following vertebroplasty or kyphoplasty. One notable aspect of Cutibacterium acnes is its role in the skin microbiome, where it is often implicated in acne development. The bacterium's presence and activity can influence skin health and disease, demonstrating the complex interactions between host, microbiota, and environmental factors. Understanding the pathogenic potential of this strain in relation to its ecological niche highlights the importance of maintaining a balanced microbiome for overall human health.