Finegoldia magna strain DSM 20470

Gram-positiveCocciNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Tissierellia

Order

Tissierellales

Family

Peptoniphilaceae

Genus

Finegoldia

Description

Finegoldia magna strain DSM 20470 is a Gram-positive, anaerobic coccus known for its association with various human infections. This bacterium is non-motile and possesses a single membrane, which is typical for many anaerobes. It thrives in mesophilic temperature ranges, making it well-suited for the human body, where it can be found in multiple habitats. F. magna is classified as free-living and has been identified as a pathogen in several serious health conditions, including endocarditis, necrotizing pneumonia, and necrotizing fasciitis. It has also been implicated in infections related to prosthetic joints and emphysematous pyelonephritis (EPN). Its presence in diverse human infections indicates its potential as an opportunistic pathogen, especially in individuals with compromised immune systems. The strain is documented under the accession number QGTH00000000.1, which allows for further study and verification of its genomic characteristics. The biological and ecological insights suggest that F. magna plays a significant role in human health, particularly in conditions that allow for its opportunistic invasion. Understanding its pathogenic mechanisms and environmental adaptability can lead to better diagnostic and therapeutic approaches for infections it may cause.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassTissierellia
OrderTissierellales
FamilyPeptoniphilaceae
GenusFinegoldia
SpeciesFinegoldia magna
Strainstrain DSM 20470

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Finegoldia magna strain DSM 20470
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Finegoldia magna strain DSM 20470 Ga0244520_160, whole genome

Gene Summary

Adenine Count

691853 bp

Thymine Count

684803 bp

Guanine Count

328174 bp

Cytosine Count

315502 bp

Genome Length

2021781 bp

Protein-coding Genes

1855 genes

Non-Coding Genes

67 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
undecaprenyl diphosphate synthaseDES33_10388Not AvailableNegative491583 - 49228727299.8
orotate phosphoribosyltransferaseDES33_10389Not AvailableNegative492415 - 49298721114.8
dihydroorotate dehydrogenase (nad+) catalytic subunitDES33_10390Not AvailableNegative492998 - 49389432448.4
dihydroorotate dehydrogenase electron transfer subunitDES33_10391Not AvailableNegative493887 - 49460326445.0
orotidine-5'-phosphate decarboxylaseDES33_10392Not AvailableNegative494596 - 49544732270.3
dihydroorotaseDES33_10393Not AvailableNegative495434 - 49663045040.0
aspartate carbamoyltransferase regulatory subunitDES33_10394Not AvailableNegative496630 - 49705816440.1
aspartate carbamoyltransferaseDES33_10395Not AvailableNegative497058 - 49797834578.7
dna-(apurinic or apyrimidinic site) lyase /endonuclease iiiDES33_10396Not AvailableNegative498047 - 49867323375.4
endonuclease ivDES33_10397Not AvailableNegative498654 - 49948731764.3

Displaying genes 481 – 490 of 1034 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Infections in human beingsCausesPMC10127037
InfectionsCausesPMC10127037
EndocarditisCausesPMC10127037
Prosthetic joint infectionsCausesPMC10127037
Necrotizing pneumoniaCausesPMC10127037
Necrotising fasciitisCausesPMC7259851
Emphysematous pyelonephritisCausesPMC7480896
EpnCausesPMC7480896
Infectious diseasesCausesPMC2650633

Displaying health effects 1 – 9 of 9 in total