Finegoldia magna strain DSM 20470

Gram-positiveCocciNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Tissierellia

Order

Tissierellales

Family

Peptoniphilaceae

Genus

Finegoldia

Description

Finegoldia magna strain DSM 20470 is a Gram-positive, anaerobic coccus known for its association with various human infections. This bacterium is non-motile and possesses a single membrane, which is typical for many anaerobes. It thrives in mesophilic temperature ranges, making it well-suited for the human body, where it can be found in multiple habitats. F. magna is classified as free-living and has been identified as a pathogen in several serious health conditions, including endocarditis, necrotizing pneumonia, and necrotizing fasciitis. It has also been implicated in infections related to prosthetic joints and emphysematous pyelonephritis (EPN). Its presence in diverse human infections indicates its potential as an opportunistic pathogen, especially in individuals with compromised immune systems. The strain is documented under the accession number QGTH00000000.1, which allows for further study and verification of its genomic characteristics. The biological and ecological insights suggest that F. magna plays a significant role in human health, particularly in conditions that allow for its opportunistic invasion. Understanding its pathogenic mechanisms and environmental adaptability can lead to better diagnostic and therapeutic approaches for infections it may cause.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassTissierellia
OrderTissierellales
FamilyPeptoniphilaceae
GenusFinegoldia
SpeciesFinegoldia magna
Strainstrain DSM 20470

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Finegoldia magna strain DSM 20470
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Finegoldia magna strain DSM 20470 Ga0244520_160, whole genome

Gene Summary

Adenine Count

691853 bp

Thymine Count

684803 bp

Guanine Count

328174 bp

Cytosine Count

315502 bp

Genome Length

2021781 bp

Protein-coding Genes

1855 genes

Non-Coding Genes

67 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
moaa/nifb/pqqe/skfb family radical sam enzymeDES33_10927Not AvailableNegative1040183 - 104158054038.0
tetr family transcriptional regulatorDES33_10928Not AvailableNegative1041731 - 104228821886.6
ahpd family alkylhydroperoxidaseDES33_10929Not AvailableNegative1042382 - 104270811518.2
phosphate abc transporter substrate-binding protein (phot family)DES33_10930Not AvailablePositive1042890 - 104384334942.0
phosphate abc transporter membrane protein 1 (phot family)DES33_10931Not AvailablePositive1043906 - 104477232589.8
phosphate abc transporter membrane protein 2 (phot family)DES33_10932Not AvailablePositive1044759 - 104561031263.9
phosphate abc transporter atp-binding protein (phot family)DES33_10933Not AvailablePositive1045588 - 104626525763.1
two-component system response regulator vanrDES33_10934Not AvailablePositive1046292 - 104699327238.1
two-component system sensor histidine kinase vansDES33_10935Not AvailablePositive1047007 - 104806841278.8
hypothetical proteinDES33_10936Not AvailablePositive1048188 - 105034783900.8

Displaying genes 1001 – 1010 of 1034 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Infections in human beingsCausesPMC10127037
InfectionsCausesPMC10127037
EndocarditisCausesPMC10127037
Prosthetic joint infectionsCausesPMC10127037
Necrotizing pneumoniaCausesPMC10127037
Necrotising fasciitisCausesPMC7259851
Emphysematous pyelonephritisCausesPMC7480896
EpnCausesPMC7480896
Infectious diseasesCausesPMC2650633

Displaying health effects 1 – 9 of 9 in total