Enterococcus faecium strain HPCN13

Gram-positiveCocciFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Enterococcaceae

Genus

Enterococcus

Description

Enterococcus faecium strain HPCN13 is a Gram-positive bacterium that is classified as a facultative anaerobe and exhibits a cocci shape. This strain is known to inhabit fermented mare milk, indicating its adaptability to specific dairy environments. It possesses true flagella, which may contribute to its motility and colonization within various hosts. HPCN13 has been identified as pathogenic to humans, associated with a range of health effects including endocarditis, nosocomial infections, bloodstream infections, urinary tract infections, biliary tract infections, and infected pancreatic necrosis. The strain is also linked to systemic infections and nosocomial bacteremia, underscoring its potential role in healthcare-associated infections. The strain has a single replicon and is capable of infecting a variety of hosts, including Homo sapiens (humans), Gallus gallus (chickens), Bos taurus (cattle), and other metazoans. This broad host range suggests that E. faecium HPCN13 could play a role in both human and veterinary health. The presence of E. faecium in fermented mare milk raises ecological considerations regarding its role in food safety and health, particularly in fermented dairy products. Given its pathogenicity, monitoring this strain in food sources is essential to prevent potential health risks associated with its consumption. Understanding its behavior in both dairy environments and host organisms can provide insights into strategies for managing infections caused by this opportunistic pathogen.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyEnterococcaceae
GenusEnterococcus
SpeciesEnterococcus faecium
Strainstrain HPCN13

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Enterococcus faecium strain HPCN13
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatfermented mare milk
Biotic relationshipNot Available
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Enterococcus faecium strain HPCN13 Scaffold_2643, whole genome

Gene Summary

Adenine Count

939426 bp

Thymine Count

984775 bp

Guanine Count

662142 bp

Cytosine Count

704683 bp

Genome Length

3291026 bp

Protein-coding Genes

4237 genes

Non-Coding Genes

126 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dihydroorotaseDKX15_01950Not AvailableNegative407690 - 40897046663.9
aspartate carbamoyltransferase catalytic subunitDKX15_01955Not AvailableNegative408989 - 40991535007.0
uracil permeaseDKX15_01960Not AvailableNegative409928 - 41121145340.0
bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase pyrrDKX15_01965Not AvailableNegative411225 - 41176420492.8
rlua family pseudouridine synthaseDKX15_01970Not AvailableNegative412000 - 41291134115.4
signal peptidase iiDKX15_01975Not AvailableNegative412908 - 41337217585.2
cbs domain-containing proteinDKX15_01980Not AvailableNegative413377 - 41407527159.2
hypothetical proteinDKX15_01985Not AvailableNegative414062 - 41444815077.7
formate--tetrahydrofolate ligaseDKX15_01990Not AvailableNegative414622 - 41629260226.0
cold-shock proteinDKX15_01995Not AvailablePositive416475 - 4167058638.98

Displaying genes 441 – 450 of 4363 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Urinary tract infectionsCausesPMC11784074
EndocarditisCausesPMC11784074
Bloodstream infectionsCausesPMC11784074
Human infectionCausesPMC6222123
Nosocomial infectionCausesPMC6222123
EndocarditisCausesPMC6385395
Infected pancreatic necrosisCausesPMC9466706
Systemic infectionCausesPMC9466706
Nosocomial infectionsCausesPMC5727370
Urinary tract infectionsCausesPMC8879582

Displaying health effects 1 – 10 of 13 in total