Legionella pneumophila strain C1

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila strain C1 is a Gram-negative, mesophilic bacterium characterized by its rod shape and aerobic metabolism. As a chemoorganotroph, it derives its energy from organic compounds. The organism is motile, possessing flagella, and typically exists as single cells rather than in clusters. This strain is significant due to its pathogenic potential in both humans and various amoebae, such as Acanthamoeba castellanii and Dictyostelium discoideum. It has been associated with serious health conditions, including pneumonia, Legionnaires' disease, and infectious endocarditis. Additionally, it can cause milder respiratory illnesses like Pontiac fever and community-acquired pneumonia (CAP). The bacterium's pathogenicity is particularly concerning for immunocompromised individuals, where it can lead to severe respiratory distress. L. pneumophila strain C1 is free-living and has a complex biotic relationship with its hosts, which include Homo sapiens and Viridiplantae. Its ability to thrive in diverse environments and its association with amoebic hosts suggest a significant ecological role. This relationship may facilitate its survival and replication in environments where it can otherwise be vulnerable. Overall, understanding the habitat and metabolic characteristics of Legionella pneumophila strain C1 can provide insights into its ecological niche and contribute to our knowledge of its pathogenic mechanisms.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainstrain C1

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila strain C1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Acanthamoeba castellanii
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Legionella pneumophila strain C1

Gene Summary

Adenine Count

1079095 bp

Thymine Count

1055336 bp

Guanine Count

638466 bp

Cytosine Count

680427 bp

Genome Length

3453324 bp

Protein-coding Genes

2988 genes

Non-Coding Genes

51 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
flagellar basal body rod protein flgcDI135_02570Not AvailableNegative577340 - 57776215493.2
flagellar basal body rod protein flgbDI135_02575Not AvailableNegative577765 - 57815714484.1
oxygen-dependent coproporphyrinogen oxidaseDI135_02580Not AvailablePositive578358 - 57930836349.8
mfs transporterDI135_02585Not AvailableNegative579412 - 58071948191.5
atpaseDI135_02590Not AvailableNegative580956 - 58151921424.5
gnat family n-acetyltransferaseDI135_02595Not AvailableNegative581577 - 58253637017.1
lysine transporter lyseDI135_02600Not AvailablePositive582790 - 58346125050.5
n-acetyltransferaseDI135_02605Not AvailableNegative583481 - 58407423233.2
phzf family phenazine biosynthesis proteinDI135_02610Not AvailableNegative584035 - 58482329482.1
marr family transcriptional regulatorDI135_02615Not AvailablePositive584901 - 58532016264.8

Displaying genes 511 – 520 of 3039 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community-acquired pneumonia (cap)CausesPMC12584241
PneumoniaCausesPMC12584241
Legionnaires' diseaseCausesPMC2653234
Legionnaires' diseaseCausesPMC3014939
Legionnaires diseaseCausesPMC4379102
Mild diseasesCausesPMC5615607
CapCausesPMC7609860
Legionnaires diseaseCausesPMC8394066
LdCausesPMC8394066
PneumoniaCausesPMC8431511

Displaying health effects 1 – 10 of 45 in total