Legionella pneumophila strain HC13

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila strain HC13 is a Gram-negative, rod-shaped bacterium that belongs to the Legionella genus. This strain is a chemoorganotroph, deriving its energy from organic compounds, and exhibits aerobic respiration. It typically exists as single cells and possesses flagella, enabling mobility. The organism is classified as mesophilic, thriving at moderate temperatures. L. pneumophila HC13 is known to be free-living and has a diverse range of hosts, including Homo sapiens, various plant species (Viridiplantae), and different amoebae such as Acanthamoeba castellanii, Balamuthia mandrillaris, and Dictyostelium discoideum. This highlights its ecological versatility and adaptation to multiple environments, including both aquatic systems and human-associated habitats. The bacterium is notable for its pathogenicity, as it is linked to various health issues in humans, including pneumonia, particularly community-acquired pneumonia (CAP), and Legionnaires' disease. Infections can range from mild respiratory illnesses to severe conditions such as infectious endocarditis and acute pneumonia. The presence of L. pneumophila HC13 in environments shared with humans underscores the importance of monitoring for this pathogen, as it can lead to outbreaks of legionellosis and other related diseases. Overall, the ecological adaptability of L. pneumophila HC13, combined with its pathogenic potential in humans, emphasizes the need for a thorough understanding of its environmental reservoirs and transmission pathways to prevent outbreaks and protect public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainstrain HC13

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila strain HC13
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Acanthamoeba castellanii
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Legionella pneumophila strain HC13


Gene Summary

Adenine Count

1060956 bp

Thymine Count

1039164 bp

Guanine Count

633430 bp

Cytosine Count

667347 bp

Genome Length

3400897 bp

Protein-coding Genes

3016 genes

Non-Coding Genes

49 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
50s ribosomal protein l3DI092_12885Not AvailableNegative2792004 - 279265122766.4
30s ribosomal protein s10DI092_12890Not AvailableNegative2792689 - 279300611938.5
elongation factor tuDI092_12895Not AvailableNegative2793012 - 279420243181.9
elongation factor gDI092_12900Not AvailableNegative2794223 - 279630777056.5
30s ribosomal protein s7DI092_12905Not AvailableNegative2796322 - 279684919792.0
30s ribosomal protein s12DI092_12910Not AvailableNegative2796870 - 279725014072.1
dna-directed rna polymerase subunit beta'DI092_12915Not AvailableNegative2797364 - 2801611157120.0
dna-directed rna polymerase subunit betaDI092_12920Not AvailableNegative2801658 - 2805764152775.0
50s ribosomal protein l7/l12DI092_12925Not AvailableNegative2805856 - 280623612911.5
50s ribosomal protein l10DI092_12930Not AvailableNegative2806267 - 280680019321.7

Displaying genes 2531 – 2540 of 3065 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community-acquired pneumonia (cap)CausesPMC12584241
PneumoniaCausesPMC12584241
Legionnaires' diseaseCausesPMC2653234
Legionnaires' diseaseCausesPMC3014939
Legionnaires diseaseCausesPMC4379102
Mild diseasesCausesPMC5615607
CapCausesPMC7609860
Legionnaires diseaseCausesPMC8394066
LdCausesPMC8394066
PneumoniaCausesPMC8431511

Displaying health effects 1 – 10 of 45 in total