Legionella pneumophila strain HC13

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila strain HC13 is a Gram-negative, rod-shaped bacterium that belongs to the Legionella genus. This strain is a chemoorganotroph, deriving its energy from organic compounds, and exhibits aerobic respiration. It typically exists as single cells and possesses flagella, enabling mobility. The organism is classified as mesophilic, thriving at moderate temperatures. L. pneumophila HC13 is known to be free-living and has a diverse range of hosts, including Homo sapiens, various plant species (Viridiplantae), and different amoebae such as Acanthamoeba castellanii, Balamuthia mandrillaris, and Dictyostelium discoideum. This highlights its ecological versatility and adaptation to multiple environments, including both aquatic systems and human-associated habitats. The bacterium is notable for its pathogenicity, as it is linked to various health issues in humans, including pneumonia, particularly community-acquired pneumonia (CAP), and Legionnaires' disease. Infections can range from mild respiratory illnesses to severe conditions such as infectious endocarditis and acute pneumonia. The presence of L. pneumophila HC13 in environments shared with humans underscores the importance of monitoring for this pathogen, as it can lead to outbreaks of legionellosis and other related diseases. Overall, the ecological adaptability of L. pneumophila HC13, combined with its pathogenic potential in humans, emphasizes the need for a thorough understanding of its environmental reservoirs and transmission pathways to prevent outbreaks and protect public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainstrain HC13

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila strain HC13
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Acanthamoeba castellanii
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Legionella pneumophila strain HC13


Gene Summary

Adenine Count

1060956 bp

Thymine Count

1039164 bp

Guanine Count

633430 bp

Cytosine Count

667347 bp

Genome Length

3400897 bp

Protein-coding Genes

3016 genes

Non-Coding Genes

49 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
preprotein translocase subunit secyDI092_12785Not AvailableNegative2782594 - 278392848966.2
50s ribosomal protein l15DI092_12790Not AvailableNegative2783925 - 278435915344.8
50s ribosomal protein l30DI092_12795Not AvailableNegative2784359 - 27845446567.21
30s ribosomal protein s5DI092_12800Not AvailableNegative2784547 - 278505317697.7
50s ribosomal protein l18DI092_12805Not AvailableNegative2785063 - 278542213007.8
50s ribosomal protein l6DI092_12810Not AvailableNegative2785433 - 278597219433.6
30s ribosomal protein s8DI092_12815Not AvailableNegative2785990 - 278638514682.2
30s ribosomal protein s14DI092_12820Not AvailableNegative2786408 - 278671011755.7
50s ribosomal protein l5DI092_12825Not AvailableNegative2786723 - 278727420939.8
50s ribosomal protein l24DI092_12830Not AvailableNegative2787290 - 278761912054.8

Displaying genes 2511 – 2520 of 3065 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community-acquired pneumonia (cap)CausesPMC12584241
PneumoniaCausesPMC12584241
Legionnaires' diseaseCausesPMC2653234
Legionnaires' diseaseCausesPMC3014939
Legionnaires diseaseCausesPMC4379102
Mild diseasesCausesPMC5615607
CapCausesPMC7609860
Legionnaires diseaseCausesPMC8394066
LdCausesPMC8394066
PneumoniaCausesPMC8431511

Displaying health effects 1 – 10 of 45 in total