Legionella pneumophila strain HH07

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila strain HH07 is a Gram-negative, mesophilic bacterium characterized by its rod shape and motility, facilitated by the presence of flagella. This strain is a chemoorganotroph, relying on organic compounds for energy, and is strictly aerobic, requiring oxygen for growth. In terms of cellular organization, it exists as singles and possesses two membranes, indicating its classification as a Gram-negative bacterium. The strain is predominantly free-living but can be associated with various hosts, including Homo sapiens (humans) and several protozoa, such as Acanthamoeba castellanii, Balamuthia mandrillaris, and Dictyostelium discoideum, as well as the plant kingdom (Viridiplantae). This diverse host range may contribute to its ecological adaptability and pathogenic potential. Legionella pneumophila strain HH07 is known for its association with several health effects, including pneumonia, particularly Legionnaires' disease, community-acquired pneumonia (CAP), and atypical pneumonia. The bacterium can lead to severe diseases, such as infectious endocarditis, highlighting its pathogenicity in both human and animal hosts. Given its ability to thrive in various environments and its connection to significant health concerns, Legionella pneumophila strain HH07 underscores the importance of monitoring water systems and environmental reservoirs where it may proliferate, particularly in urban settings where interactions with human populations are likely. Understanding its ecological and biological traits is crucial for developing effective prevention and control strategies against its associated diseases.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainstrain HH07

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila strain HH07
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Acanthamoeba castellanii
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Legionella pneumophila strain HH07

Gene Summary

Adenine Count

1063843 bp

Thymine Count

1029828 bp

Guanine Count

617184 bp

Cytosine Count

678965 bp

Genome Length

3389820 bp

Protein-coding Genes

3005 genes

Non-Coding Genes

49 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
acetyl coa carboxylase subunit alphaDI089_03175Not AvailableNegative736146 - 73758552750.1
3-oxoacyl-acp synthaseDI089_03180Not AvailablePositive737794 - 73885539192.8
fatty acyl-amp ligaseDI089_03185Not AvailablePositive738867 - 74061266041.6
long-chain fatty acid--coa ligaseDI089_03190Not AvailablePositive740602 - 74199651396.0
acyl carrier proteinDI089_03195Not AvailablePositive741986 - 7422198872.99
sdr family nad(p)-dependent oxidoreductaseDI089_03200Not AvailablePositive742216 - 74296827473.4
ketoacyl-acp synthase iiiDI089_03205Not AvailablePositive742965 - 74397536043.0
acyl carrier proteinDI089_03210Not AvailableNegative744318 - 7445458636.15
bcr/cfla family drug resistance efflux transporterDI089_03215Not AvailableNegative744555 - 74592249621.0
sterol desaturase family proteinDI089_03220Not AvailablePositive745932 - 74713446544.6

Displaying genes 631 – 640 of 3054 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community-acquired pneumonia (cap)CausesPMC12584241
PneumoniaCausesPMC12584241
Legionnaires' diseaseCausesPMC2653234
Legionnaires' diseaseCausesPMC3014939
Legionnaires diseaseCausesPMC4379102
Mild diseasesCausesPMC5615607
CapCausesPMC7609860
Legionnaires diseaseCausesPMC8394066
LdCausesPMC8394066
PneumoniaCausesPMC8431511

Displaying health effects 1 – 10 of 45 in total