Legionella pneumophila strain HH26

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila strain HH26 is a Gram-negative bacterium characterized as a mesophilic, aerobic, chemoorganotroph. This strain typically exists in a singles arrangement and possesses flagella, which contributes to its mobility. With a single replicon and a double membrane structure, HH26 showcases typical features of the Legionella genus. This bacterium is primarily free-living but is also associated with various hosts, including Homo sapiens, Viridiplantae, and several amoeboid organisms such as Acanthamoeba castellanii and Dictyostelium discoideum. It is noteworthy for its pathogenicity in humans, causing a range of health issues from mild diseases to serious conditions such as community-acquired pneumonia (CAP), Legionnaires' disease, and infectious endocarditis. The ecological role of Legionella pneumophila strain HH26 is significant, as it thrives in environments where it can interact with amoebae, which serve as a natural reservoir. This relationship enhances its survival and potential for pathogenicity, particularly in human hosts. The bacterium's ability to infect both human and animal hosts underscores its ecological adaptability and highlights the importance of monitoring its presence in water systems to prevent outbreaks of legionellosis. Understanding this organism's biology and ecology is crucial for developing effective strategies to mitigate the health risks associated with Legionella infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainstrain HH26

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila strain HH26
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Acanthamoeba castellanii
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Legionella pneumophila strain HH26

Gene Summary

Adenine Count

1053381 bp

Thymine Count

1048726 bp

Guanine Count

643714 bp

Cytosine Count

658432 bp

Genome Length

3404253 bp

Protein-coding Genes

0 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
tolc family proteinDI013_13580Not AvailableNegative2960153 - 296155053392.6
rnd transporterDI013_13585Not AvailableNegative2961547 - 296253337301.1
abc transporter atp-binding proteinDI013_13590Not AvailableNegative2962530 - 296411960038.0
lysr family transcriptional regulatorDI013_13595Not AvailableNegative2964161 - 296501232021.1
oxidoreductaseDI013_13600Not AvailablePositive2965114 - 296663456255.4
duf2309 domain-containing proteinDI013_13605Not AvailablePositive2966649 - 296893787013.8
transcriptional regulatorDI013_13610Not AvailablePositive2968951 - 296930412947.0
hypothetical proteinDI013_13615Not AvailablePositive2969314 - 297016832298.7
5-(carboxyamino)imidazole ribonucleotide mutaseDI013_13620Not AvailablePositive2970228 - 297072817568.4
5-(carboxyamino)imidazole ribonucleotide synthaseDI013_13625Not AvailablePositive2970725 - 297180439992.2

Displaying genes 2661 – 2670 of 3063 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community-acquired pneumonia (cap)CausesPMC12584241
PneumoniaCausesPMC12584241
Legionnaires' diseaseCausesPMC2653234
Legionnaires' diseaseCausesPMC3014939
Legionnaires diseaseCausesPMC4379102
Mild diseasesCausesPMC5615607
CapCausesPMC7609860
Legionnaires diseaseCausesPMC8394066
LdCausesPMC8394066
PneumoniaCausesPMC8431511

Displaying health effects 1 – 10 of 45 in total