Legionella pneumophila strain HH26

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila strain HH26 is a Gram-negative bacterium characterized as a mesophilic, aerobic, chemoorganotroph. This strain typically exists in a singles arrangement and possesses flagella, which contributes to its mobility. With a single replicon and a double membrane structure, HH26 showcases typical features of the Legionella genus. This bacterium is primarily free-living but is also associated with various hosts, including Homo sapiens, Viridiplantae, and several amoeboid organisms such as Acanthamoeba castellanii and Dictyostelium discoideum. It is noteworthy for its pathogenicity in humans, causing a range of health issues from mild diseases to serious conditions such as community-acquired pneumonia (CAP), Legionnaires' disease, and infectious endocarditis. The ecological role of Legionella pneumophila strain HH26 is significant, as it thrives in environments where it can interact with amoebae, which serve as a natural reservoir. This relationship enhances its survival and potential for pathogenicity, particularly in human hosts. The bacterium's ability to infect both human and animal hosts underscores its ecological adaptability and highlights the importance of monitoring its presence in water systems to prevent outbreaks of legionellosis. Understanding this organism's biology and ecology is crucial for developing effective strategies to mitigate the health risks associated with Legionella infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainstrain HH26

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila strain HH26
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Acanthamoeba castellanii
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Legionella pneumophila strain HH26

Gene Summary

Adenine Count

1053381 bp

Thymine Count

1048726 bp

Guanine Count

643714 bp

Cytosine Count

658432 bp

Genome Length

3404253 bp

Protein-coding Genes

0 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
succinyl-diaminopimelate desuccinylaseDI013_10895Not AvailableNegative2410783 - 241191641495.8
2,3,4,5-tetrahydropyridine-2,6-dicarboxylate n-succinyltransferaseDI013_10900Not AvailableNegative2411909 - 241273930008.0
acyltransferaseDI013_10905Not AvailableNegative2412743 - 241363634557.7
cystathionine beta-lyaseDI013_10910Not AvailableNegative2413703 - 241485442022.6
ggdef domain-containing proteinDI013_10915Not AvailablePositive2415003 - 241731888684.6
fad-dependent monooxygenaseDI013_10920Not AvailablePositive2417620 - 241896951347.8
hypothetical proteinDI013_10925Not AvailablePositive2419174 - 241993830049.9
fad-binding proteinDI013_10930Not AvailablePositive2419895 - 242126551495.1
general secretion pathway protein gspcDI013_10935Not AvailablePositive2421615 - 242212418929.1
sel1 repeat family proteinDI013_10940Not AvailablePositive2422130 - 242250714473.7

Displaying genes 2141 – 2150 of 3063 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community-acquired pneumonia (cap)CausesPMC12584241
PneumoniaCausesPMC12584241
Legionnaires' diseaseCausesPMC2653234
Legionnaires' diseaseCausesPMC3014939
Legionnaires diseaseCausesPMC4379102
Mild diseasesCausesPMC5615607
CapCausesPMC7609860
Legionnaires diseaseCausesPMC8394066
LdCausesPMC8394066
PneumoniaCausesPMC8431511

Displaying health effects 1 – 10 of 45 in total