Legionella pneumophila strain HH31

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila strain HH31 is a pathogenic, Gram-negative bacterium that exhibits a rod shape and is motile due to the presence of flagella. This strain is classified as a chemoorganotroph, relying on organic compounds for energy, and is capable of aerobic respiration. It has a mesophilic temperature range, thriving in moderate temperature conditions. L. pneumophila strain HH31 is predominantly free-living but is also associated with various hosts, including humans (Homo sapiens), plants (Viridiplantae), and a variety of amoebae such as Acanthamoeba castellanii, Balamuthia mandrillaris, and Dictyostelium discoideum. The bacterium possesses a single replicon and is characterized by a double membrane structure. This strain is known for its pathogenicity in humans, causing conditions such as pneumonia, including community-acquired pneumonia (CAP) and Legionnaires' disease, as well as mild diseases like Pontiac fever. Its ability to infect a wide range of hosts, particularly amoebae, highlights its ecological versatility and adaptation strategies, which may play a role in its survival and proliferation in various environments. The interaction between L. pneumophila strain HH31 and its diverse hosts underscores the importance of understanding its ecological relationships, especially in contexts related to water systems where it may thrive and pose health risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainstrain HH31

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila strain HH31
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Acanthamoeba castellanii
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Legionella pneumophila strain HH31

Gene Summary

Adenine Count

1056057 bp

Thymine Count

1038274 bp

Guanine Count

630066 bp

Cytosine Count

666830 bp

Genome Length

3391227 bp

Protein-coding Genes

3007 genes

Non-Coding Genes

49 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
alpha/beta hydrolaseDI039_04530Not AvailablePositive1013149 - 101449550721.0
carboxymuconolactone decarboxylase family proteinDI039_04535Not AvailableNegative1014522 - 101507921393.0
non-canonical purine ntp pyrophosphataseDI039_04540Not AvailablePositive1015128 - 101571221005.3
tetratricopeptide repeat proteinDI039_04545Not AvailablePositive1015714 - 101742965255.8
phosphomannomutase/phosphoglucomutaseDI039_04550Not AvailableNegative1017747 - 101913551391.8
dutp diphosphataseDI039_04555Not AvailableNegative1019136 - 101959416347.7
bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase coabcDI039_04560Not AvailableNegative1019621 - 102081743253.5
jab domain-containing proteinDI039_04565Not AvailablePositive1020894 - 102157725750.9
hypothetical proteinDI039_04570Not AvailablePositive1021613 - 10218499003.4
type iv secretion protein dotDI039_04575Not AvailablePositive1021929 - 1025813148760.0

Displaying genes 891 – 900 of 3056 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community-acquired pneumonia (cap)CausesPMC12584241
PneumoniaCausesPMC12584241
Legionnaires' diseaseCausesPMC2653234
Legionnaires' diseaseCausesPMC3014939
Legionnaires diseaseCausesPMC4379102
Mild diseasesCausesPMC5615607
CapCausesPMC7609860
Legionnaires diseaseCausesPMC8394066
LdCausesPMC8394066
PneumoniaCausesPMC8431511

Displaying health effects 1 – 10 of 45 in total