Legionella pneumophila strain HH31

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila strain HH31 is a pathogenic, Gram-negative bacterium that exhibits a rod shape and is motile due to the presence of flagella. This strain is classified as a chemoorganotroph, relying on organic compounds for energy, and is capable of aerobic respiration. It has a mesophilic temperature range, thriving in moderate temperature conditions. L. pneumophila strain HH31 is predominantly free-living but is also associated with various hosts, including humans (Homo sapiens), plants (Viridiplantae), and a variety of amoebae such as Acanthamoeba castellanii, Balamuthia mandrillaris, and Dictyostelium discoideum. The bacterium possesses a single replicon and is characterized by a double membrane structure. This strain is known for its pathogenicity in humans, causing conditions such as pneumonia, including community-acquired pneumonia (CAP) and Legionnaires' disease, as well as mild diseases like Pontiac fever. Its ability to infect a wide range of hosts, particularly amoebae, highlights its ecological versatility and adaptation strategies, which may play a role in its survival and proliferation in various environments. The interaction between L. pneumophila strain HH31 and its diverse hosts underscores the importance of understanding its ecological relationships, especially in contexts related to water systems where it may thrive and pose health risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainstrain HH31

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila strain HH31
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Acanthamoeba castellanii
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Legionella pneumophila strain HH31

Gene Summary

Adenine Count

1056057 bp

Thymine Count

1038274 bp

Guanine Count

630066 bp

Cytosine Count

666830 bp

Genome Length

3391227 bp

Protein-coding Genes

3007 genes

Non-Coding Genes

49 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
type iv pilus secretin pilqDI039_11120Not AvailablePositive2452929 - 245502577446.3
shikimate kinaseDI039_11125Not AvailablePositive2455470 - 245599719829.7
3-dehydroquinate synthaseDI039_11130Not AvailablePositive2455984 - 245709340981.0
hypothetical proteinDI039_11135Not AvailablePositive2457090 - 245854154343.6
universal stress proteinDI039_11140Not AvailablePositive2458650 - 245908115763.0
bifunctional riboflavin kinase/fad synthetaseDI039_11145Not AvailablePositive2459205 - 246019136969.9
isoleucine--trna ligaseDI039_11150Not AvailablePositive2460304 - 2463099105901.0
lipoprotein signal peptidaseDI039_11155Not AvailablePositive2463096 - 246356017483.8
multidrug dmt transporter permeaseDI039_11160Not AvailableNegative2463857 - 246442020374.6
lidaDI039_11165Not AvailableNegative2464601 - 246679083192.0

Displaying genes 2191 – 2200 of 3056 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community-acquired pneumonia (cap)CausesPMC12584241
PneumoniaCausesPMC12584241
Legionnaires' diseaseCausesPMC2653234
Legionnaires' diseaseCausesPMC3014939
Legionnaires diseaseCausesPMC4379102
Mild diseasesCausesPMC5615607
CapCausesPMC7609860
Legionnaires diseaseCausesPMC8394066
LdCausesPMC8394066
PneumoniaCausesPMC8431511

Displaying health effects 1 – 10 of 45 in total