Legionella pneumophila strain HH48

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila strain HH48 is a Gram-negative, rod-shaped bacterium that is classified as a chemoorganotroph, deriving its energy from organic compounds. This strain is notable for its aerobic nature and is capable of movement, thanks to the presence of flagella. It exists as a single cell and has a mesophilic temperature range, indicating optimal growth at moderate temperatures. The bacterium is uniquely associated with various hosts, including Homo sapiens (humans), Viridiplantae (plants), and several amoebae species such as Acanthamoeba castellanii and Balamuthia mandrillaris. This versatility in host associations highlights its ecological adaptability. L. pneumophila strain HH48 is known for its pathogenicity, particularly in humans, where it can cause a range of serious health effects, including pneumonia, infectious endocarditis, and Legionnaires' disease, a severe form of pneumonia. In terms of its cellular structure, L. pneumophila strain HH48 has two membranes and a single replicon, which is characteristic of many Gram-negative bacteria. The relationship it maintains within its environment is free-living, suggesting it can exist independently while also indicating a complex interaction with host organisms. The ability of L. pneumophila strain HH48 to thrive in various ecological niches and cause significant health issues underscores the importance of monitoring and understanding this pathogen, particularly in water systems where it can proliferate and pose a risk to human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainstrain HH48

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila strain HH48
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Acanthamoeba castellanii
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Legionella pneumophila strain HH48 NODE_37_length_221_cov_52.0532,

Gene Summary

Adenine Count

1056851 bp

Thymine Count

1039092 bp

Guanine Count

631335 bp

Cytosine Count

668159 bp

Genome Length

3395437 bp

Protein-coding Genes

3024 genes

Non-Coding Genes

49 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
sodium-independent anion transporterDIZ96_10465Not AvailablePositive2326262 - 232796561151.1
acyl-coa dehydrogenaseDIZ96_10470Not AvailableNegative2328167 - 232987064543.6
linear amide c-n hydrolaseDIZ96_10475Not AvailableNegative2330097 - 233109536871.0
phosphoenolpyruvate synthaseDIZ96_10480Not AvailablePositive2331320 - 233370787714.2
cation:proton antiporterDIZ96_10485Not AvailablePositive2333951 - 233539052170.5
carboxylating nicotinate-nucleotide diphosphorylaseDIZ96_10490Not AvailablePositive2335387 - 233622930870.3
undecaprenyldiphospho-muramoylpentapeptide beta-n- acetylglucosaminyltransferaseDIZ96_10495Not AvailablePositive2336226 - 233731739684.6
peptidase m20DIZ96_10500Not AvailablePositive2337292 - 233870752535.1
competence protein comeaDIZ96_10505Not AvailablePositive2338799 - 233911611774.5
rod shape-determining proteinDIZ96_10510Not AvailablePositive2339312 - 234034936955.9

Displaying genes 2061 – 2070 of 3073 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community-acquired pneumonia (cap)CausesPMC12584241
PneumoniaCausesPMC12584241
Legionnaires' diseaseCausesPMC2653234
Legionnaires' diseaseCausesPMC3014939
Legionnaires diseaseCausesPMC4379102
Mild diseasesCausesPMC5615607
CapCausesPMC7609860
Legionnaires diseaseCausesPMC8394066
LdCausesPMC8394066
PneumoniaCausesPMC8431511

Displaying health effects 1 – 10 of 45 in total