Legionella pneumophila strain HH48

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila strain HH48 is a Gram-negative, rod-shaped bacterium that is classified as a chemoorganotroph, deriving its energy from organic compounds. This strain is notable for its aerobic nature and is capable of movement, thanks to the presence of flagella. It exists as a single cell and has a mesophilic temperature range, indicating optimal growth at moderate temperatures. The bacterium is uniquely associated with various hosts, including Homo sapiens (humans), Viridiplantae (plants), and several amoebae species such as Acanthamoeba castellanii and Balamuthia mandrillaris. This versatility in host associations highlights its ecological adaptability. L. pneumophila strain HH48 is known for its pathogenicity, particularly in humans, where it can cause a range of serious health effects, including pneumonia, infectious endocarditis, and Legionnaires' disease, a severe form of pneumonia. In terms of its cellular structure, L. pneumophila strain HH48 has two membranes and a single replicon, which is characteristic of many Gram-negative bacteria. The relationship it maintains within its environment is free-living, suggesting it can exist independently while also indicating a complex interaction with host organisms. The ability of L. pneumophila strain HH48 to thrive in various ecological niches and cause significant health issues underscores the importance of monitoring and understanding this pathogen, particularly in water systems where it can proliferate and pose a risk to human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainstrain HH48

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila strain HH48
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Acanthamoeba castellanii
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Legionella pneumophila strain HH48 NODE_37_length_221_cov_52.0532,

Gene Summary

Adenine Count

1056851 bp

Thymine Count

1039092 bp

Guanine Count

631335 bp

Cytosine Count

668159 bp

Genome Length

3395437 bp

Protein-coding Genes

3024 genes

Non-Coding Genes

49 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
eama/rhat family transporterDIZ96_08805Not AvailablePositive1973507 - 197440332448.0
hypothetical proteinDIZ96_08810Not AvailablePositive1974407 - 197468810502.0
sulfurtransferaseDIZ96_08815Not AvailablePositive1974675 - 197502513408.2
hypothetical proteinDIZ96_08820Not AvailableNegative1975049 - 197571125372.2
pglz domain-containing proteinDIZ96_08825Not AvailablePositive1976057 - 197771862337.3
uridine kinaseDIZ96_08830Not AvailablePositive1977687 - 197840927864.0
enoyl-acp reductaseDIZ96_08835Not AvailablePositive1978505 - 197931128467.9
peptidylprolyl isomeraseDIZ96_08840Not AvailableNegative1979849 - 198172371784.0
Trna-aspNot AvailableNot AvailablePositive1981815 - 1981891Not Available
Trna-valNot AvailableNot AvailablePositive1981898 - 1981973Not Available

Displaying genes 1731 – 1740 of 3073 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community-acquired pneumonia (cap)CausesPMC12584241
PneumoniaCausesPMC12584241
Legionnaires' diseaseCausesPMC2653234
Legionnaires' diseaseCausesPMC3014939
Legionnaires diseaseCausesPMC4379102
Mild diseasesCausesPMC5615607
CapCausesPMC7609860
Legionnaires diseaseCausesPMC8394066
LdCausesPMC8394066
PneumoniaCausesPMC8431511

Displaying health effects 1 – 10 of 45 in total