Legionella pneumophila strain RC05

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila strain RC05 is a Gram-negative, rod-shaped bacterium that exhibits aerobic metabolism as a chemoorganotroph. This strain is notable for its single-cell arrangement and possesses flagella, which contribute to its mobility. Legionella pneumophila is classified as mesophilic, indicating that it thrives in moderate temperature ranges. The habitat of strain RC05 is primarily host-associated, being free-living but also capable of infecting a variety of hosts, including Homo sapiens, certain plants (Viridiplantae), and multiple amoebae species such as Acanthamoeba castellanii and Balamuthia mandrillaris. This ability to inhabit diverse hosts may enhance its survival and adaptability in various environments. Legionella pneumophila is known for its pathogenicity, particularly in humans, where it can cause severe health effects including pneumonia, endocarditis, and Legionnaires' disease. These diseases often manifest as community-acquired pneumonia (CAP) and can range from mild to acute infections. In summary, the ecological versatility of Legionella pneumophila strain RC05, with its capacity to interact with both free-living and host-associated environments, underscores the importance of monitoring this bacterium in public health contexts. Its potential to cause serious illnesses in humans, coupled with its presence in diverse ecological niches, highlights the need for continued research and vigilance regarding its transmission pathways and environmental reservoirs.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainstrain RC05

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila strain RC05
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Acanthamoeba castellanii
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Legionella pneumophila strain RC05

Gene Summary

Adenine Count

1132474 bp

Thymine Count

1135657 bp

Guanine Count

705736 bp

Cytosine Count

703222 bp

Genome Length

3677089 bp

Protein-coding Genes

3282 genes

Non-Coding Genes

51 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lrp/asnc family transcriptional regulatorDIZ58_03720Not AvailablePositive825339 - 82581217584.7
hypothetical proteinDIZ58_03725Not AvailablePositive826009 - 82635012174.0
hypothetical proteinDIZ58_03730Not AvailablePositive826541 - 82710121836.0
hypothetical proteinDIZ58_03735Not AvailableNegative827194 - 82756214206.8
duf1328 domain-containing proteinDIZ58_03740Not AvailablePositive827782 - 8279616285.33
metal-activated pyridoxal enzymeDIZ58_03745Not AvailableNegative828002 - 82913242253.9
hypothetical proteinDIZ58_03755Not AvailableNegative829964 - 83132850628.0
type iv secretion protein dotDIZ58_03760Not AvailableNegative831673 - 83334664258.1
alpha-amylaseDIZ58_03765Not AvailablePositive833513 - 83506359899.2
hypothetical proteinDIZ58_03770Not AvailableNegative835221 - 83693966059.1

Displaying genes 741 – 750 of 3333 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community-acquired pneumonia (cap)CausesPMC12584241
PneumoniaCausesPMC12584241
Legionnaires' diseaseCausesPMC2653234
Legionnaires' diseaseCausesPMC3014939
Legionnaires diseaseCausesPMC4379102
Mild diseasesCausesPMC5615607
CapCausesPMC7609860
Legionnaires diseaseCausesPMC8394066
LdCausesPMC8394066
PneumoniaCausesPMC8431511

Displaying health effects 1 – 10 of 45 in total