Legionella pneumophila strain RC07

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila strain RC07 is a Gram-negative, rod-shaped bacterium that exhibits aerobic respiration and is classified as a chemoorganotroph, utilizing organic compounds as its energy source. This strain is motile, characterized by the presence of flagella, and typically exists as single cells rather than in clusters. It is a mesophilic organism, thriving in moderate temperature conditions. L. pneumophila strain RC07 is primarily host-associated, indicating that it relies on various hosts for survival and proliferation. Notable hosts include Homo sapiens, various amoebae such as Acanthamoeba castellanii and Balamuthia mandrillaris, as well as the slime mold Dictyostelium discoideum. Its biotic relationship is free-living, which allows it to inhabit diverse environments, particularly those associated with water systems. This strain is known for its pathogenicity in humans, being responsible for several health issues, including Legionnaires' disease, community-acquired pneumonia, and other forms of pneumonia and endocarditis. The bacterium's ability to infect both humans and animals emphasizes its role in environmental and health contexts. The presence of L. pneumophila strain RC07 in various aquatic environments and its association with amoebae suggest a complex ecological interplay. The interaction between the bacterium and its protozoan hosts may facilitate its survival in natural water systems, while also posing a significant risk to human health through aerosolized water droplets or contaminated water sources. Understanding these dynamics is crucial for managing outbreaks and preventing infections associated with this pathogen.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainstrain RC07

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila strain RC07
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Acanthamoeba castellanii
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Legionella pneumophila strain RC07

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

2937 genes

Non-Coding Genes

400 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
outer membrane protein assembly factor bamdDIZ56_00130Not AvailablePositive31673 - 3244629514.4
recombination-associated protein rdgcDIZ56_00135Not AvailableNegative32594 - 3353835937.6
potassium transporter kupDIZ56_00140Not AvailableNegative33650 - 3554570638.1
hypothetical proteinDIZ56_00145Not AvailableNegative35552 - 3655336646.5
class i sam-dependent rrna methyltransferaseDIZ56_00150Not AvailablePositive36613 - 3778543431.3
glycosyl hydrolaseDIZ56_00155Not AvailablePositive37871 - 3905844686.0
dj-1/pfpi family proteinDIZ56_00160Not AvailablePositive39166 - 3992128451.4
bifunctional phosphoribosyl-amp cyclohydrolase/phosphoribosyl-atp diphosphatase hisieDIZ56_00165Not AvailableNegative40010 - 4063323077.6
imidazole glycerol phosphate synthase subunit hisfDIZ56_00170Not AvailableNegative40630 - 4139728165.9
1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomeraseDIZ56_00175Not AvailableNegative41391 - 4211026285.1

Displaying genes 31 – 40 of 3337 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community-acquired pneumonia (cap)CausesPMC12584241
PneumoniaCausesPMC12584241
Legionnaires' diseaseCausesPMC2653234
Legionnaires' diseaseCausesPMC3014939
Legionnaires diseaseCausesPMC4379102
Mild diseasesCausesPMC5615607
CapCausesPMC7609860
Legionnaires diseaseCausesPMC8394066
LdCausesPMC8394066
PneumoniaCausesPMC8431511

Displaying health effects 1 – 10 of 45 in total