Legionella pneumophila strain RD04

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila strain RD04 is a gram-negative, rod-shaped bacterium that thrives in aerobic environments. As a chemoorganotroph, it utilizes organic compounds for energy, and it exhibits mobility due to the presence of flagella. This strain is mesophilic, indicating it prefers moderate temperature conditions for optimal growth. Legionella pneumophila RD04 is primarily host-associated, existing in a free-living biotic relationship with various hosts, including Homo sapiens, Viridiplantae, and several amoebae such as Acanthamoeba castellanii and Balamuthia mandrillaris. The bacterium has a singular replicon and is characterized by a double membrane structure. It is important to note the health implications associated with this strain, as it is known to cause a range of diseases in humans, including pneumonia, particularly community-acquired pneumonia (CAP), and Legionnaires' disease. This strain can lead to severe health issues such as endocarditis and other forms of pneumonia, making it a significant pathogen in public health contexts. Given its ecological interactions and pathogenic potential, Legionella pneumophila RD04 exemplifies the complex relationships between environmental microorganisms and their hosts. Understanding its habitat and pathogenicity is crucial for developing effective strategies for prevention and control of legionellosis in human populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainstrain RD04

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila strain RD04
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Acanthamoeba castellanii
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Legionella pneumophila strain RD04

Gene Summary

Adenine Count

1115599 bp

Thymine Count

1126268 bp

Guanine Count

695765 bp

Cytosine Count

696510 bp

Genome Length

3634142 bp

Protein-coding Genes

3233 genes

Non-Coding Genes

50 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
s41 family peptidaseDIZ57_04870Not AvailablePositive1078358 - 107969548118.2
amino acid-binding proteinDIZ57_04875Not AvailableNegative1079768 - 108094344613.9
adenosine deaminaseDIZ57_04880Not AvailablePositive1081058 - 108253355850.5
ornithine carbamoyltransferaseDIZ57_04885Not AvailableNegative1082622 - 108373741478.6
argininosuccinate lyaseDIZ57_04890Not AvailableNegative1083740 - 108506549858.4
argininosuccinate synthaseDIZ57_04895Not AvailableNegative1084968 - 108618545005.0
amino acid abc transporter atp-binding proteinDIZ57_04900Not AvailableNegative1086182 - 108685024303.7
amino acid abc transporter permeaseDIZ57_04905Not AvailableNegative1086834 - 108749924430.0
amino acid abc transporter substrate-binding proteinDIZ57_04910Not AvailableNegative1087478 - 108821226862.3
argr family transcriptional regulatorDIZ57_04915Not AvailablePositive1088343 - 108880117060.7

Displaying genes 971 – 980 of 3283 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community-acquired pneumonia (cap)CausesPMC12584241
PneumoniaCausesPMC12584241
Legionnaires' diseaseCausesPMC2653234
Legionnaires' diseaseCausesPMC3014939
Legionnaires diseaseCausesPMC4379102
Mild diseasesCausesPMC5615607
CapCausesPMC7609860
Legionnaires diseaseCausesPMC8394066
LdCausesPMC8394066
PneumoniaCausesPMC8431511

Displaying health effects 1 – 10 of 45 in total