Legionella pneumophila strain RD04

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila strain RD04 is a gram-negative, rod-shaped bacterium that thrives in aerobic environments. As a chemoorganotroph, it utilizes organic compounds for energy, and it exhibits mobility due to the presence of flagella. This strain is mesophilic, indicating it prefers moderate temperature conditions for optimal growth. Legionella pneumophila RD04 is primarily host-associated, existing in a free-living biotic relationship with various hosts, including Homo sapiens, Viridiplantae, and several amoebae such as Acanthamoeba castellanii and Balamuthia mandrillaris. The bacterium has a singular replicon and is characterized by a double membrane structure. It is important to note the health implications associated with this strain, as it is known to cause a range of diseases in humans, including pneumonia, particularly community-acquired pneumonia (CAP), and Legionnaires' disease. This strain can lead to severe health issues such as endocarditis and other forms of pneumonia, making it a significant pathogen in public health contexts. Given its ecological interactions and pathogenic potential, Legionella pneumophila RD04 exemplifies the complex relationships between environmental microorganisms and their hosts. Understanding its habitat and pathogenicity is crucial for developing effective strategies for prevention and control of legionellosis in human populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainstrain RD04

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila strain RD04
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Acanthamoeba castellanii
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Legionella pneumophila strain RD04

Gene Summary

Adenine Count

1115599 bp

Thymine Count

1126268 bp

Guanine Count

695765 bp

Cytosine Count

696510 bp

Genome Length

3634142 bp

Protein-coding Genes

3233 genes

Non-Coding Genes

50 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
bifunctionalDIZ57_01890Not AvailablePositive424131 - 426872105854.0
alpha/beta hydrolaseDIZ57_01900Not AvailablePositive427081 - 42834948550.7
hlyd family secretion proteinDIZ57_01905Not AvailablePositive428417 - 42898921691.4
abc transporter atp-binding proteinDIZ57_01910Not AvailablePositive428967 - 42990835207.1
abc transporter permeaseDIZ57_01915Not AvailablePositive429923 - 43104141850.4
30s ribosomal protein s12 methylthiotransferase rimoDIZ57_01920Not AvailableNegative431111 - 43243048990.8
protein-disulfide reductase dsbdDIZ57_01925Not AvailableNegative432520 - 43431065404.8
co-chaperone groesDIZ57_01930Not AvailablePositive434466 - 43475610475.9
chaperonin groelDIZ57_01935Not AvailablePositive434778 - 43643058382.9
dna starvation/stationary phase protection proteinDIZ57_01940Not AvailablePositive436553 - 43699316577.9

Displaying genes 381 – 390 of 3283 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community-acquired pneumonia (cap)CausesPMC12584241
PneumoniaCausesPMC12584241
Legionnaires' diseaseCausesPMC2653234
Legionnaires' diseaseCausesPMC3014939
Legionnaires diseaseCausesPMC4379102
Mild diseasesCausesPMC5615607
CapCausesPMC7609860
Legionnaires diseaseCausesPMC8394066
LdCausesPMC8394066
PneumoniaCausesPMC8431511

Displaying health effects 1 – 10 of 45 in total