Legionella pneumophila strain RD04

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila strain RD04 is a gram-negative, rod-shaped bacterium that thrives in aerobic environments. As a chemoorganotroph, it utilizes organic compounds for energy, and it exhibits mobility due to the presence of flagella. This strain is mesophilic, indicating it prefers moderate temperature conditions for optimal growth. Legionella pneumophila RD04 is primarily host-associated, existing in a free-living biotic relationship with various hosts, including Homo sapiens, Viridiplantae, and several amoebae such as Acanthamoeba castellanii and Balamuthia mandrillaris. The bacterium has a singular replicon and is characterized by a double membrane structure. It is important to note the health implications associated with this strain, as it is known to cause a range of diseases in humans, including pneumonia, particularly community-acquired pneumonia (CAP), and Legionnaires' disease. This strain can lead to severe health issues such as endocarditis and other forms of pneumonia, making it a significant pathogen in public health contexts. Given its ecological interactions and pathogenic potential, Legionella pneumophila RD04 exemplifies the complex relationships between environmental microorganisms and their hosts. Understanding its habitat and pathogenicity is crucial for developing effective strategies for prevention and control of legionellosis in human populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainstrain RD04

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila strain RD04
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Acanthamoeba castellanii
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Legionella pneumophila strain RD04

Gene Summary

Adenine Count

1115599 bp

Thymine Count

1126268 bp

Guanine Count

695765 bp

Cytosine Count

696510 bp

Genome Length

3634142 bp

Protein-coding Genes

3233 genes

Non-Coding Genes

50 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cell division protein zapaDIZ57_10640Not AvailableNegative2295745 - 229605911936.6
yeca family proteinDIZ57_10645Not AvailablePositive2296215 - 229679621758.3
xaa-pro aminopeptidaseDIZ57_10650Not AvailablePositive2296884 - 229821249723.7
2-octaprenyl-6-methoxyphenyl hydroxylaseDIZ57_10655Not AvailablePositive2298202 - 229940443943.7
fad-dependent oxidoreductaseDIZ57_10660Not AvailablePositive2299401 - 230056443025.1
alpha-l-glutamate ligase-like proteinDIZ57_10665Not AvailableNegative2300892 - 230183935068.6
hypothetical proteinDIZ57_10670Not AvailableNegative2301836 - 230335956660.8
hypothetical proteinDIZ57_10675Not AvailableNegative2303349 - 230387619442.0
hypothetical proteinDIZ57_10680Not AvailablePositive2304105 - 230605173140.7
duf4254 domain-containing proteinDIZ57_10685Not AvailableNegative2306017 - 230660723452.9

Displaying genes 2091 – 2100 of 3283 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community-acquired pneumonia (cap)CausesPMC12584241
PneumoniaCausesPMC12584241
Legionnaires' diseaseCausesPMC2653234
Legionnaires' diseaseCausesPMC3014939
Legionnaires diseaseCausesPMC4379102
Mild diseasesCausesPMC5615607
CapCausesPMC7609860
Legionnaires diseaseCausesPMC8394066
LdCausesPMC8394066
PneumoniaCausesPMC8431511

Displaying health effects 1 – 10 of 45 in total