Legionella pneumophila strain RH06

Gram-negativeRodMotileAerobic

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Legionellales

Family

Legionellaceae

Genus

Legionella

Description

Legionella pneumophila strain RH06 is a Gram-negative, rod-shaped bacterium that exhibits aerobic respiration and belongs to the category of chemoorganotrophs, utilizing organic compounds as energy sources. This strain is characterized as free-living and has been identified in various hosts, including Homo sapiens, members of the Viridiplantae, and several amoeba species such as Acanthamoeba castellanii and Dictyostelium discoideum. The organism is motile, possessing flagella, which aids in its movement within aquatic environments. Legionella pneumophila strain RH06 is mesophilic, thriving in moderate temperature ranges. It features a cellular structure with two membranes and contains a single replicon, which is typical for this genus. This strain is notably pathogenic, associated with a range of serious health effects, including pneumonia and various forms of endocarditis, such as infectious and community-acquired pneumonia. Legionella pneumophila is the causative agent of Legionnaires' disease, which can manifest as acute pneumonia and has been linked to epidemic outbreaks. Other reported conditions include atypical pneumonia, Pontiac fever, and legionellosis, indicating its significant impact on public health. Ecologically, the presence of Legionella pneumophila strain RH06 in both human and environmental contexts suggests a complex interaction with its hosts, particularly amoebae, which may serve as reservoirs and protective niches for the bacterium. This relationship underscores the importance of understanding the ecological dynamics of Legionella spp. to mitigate their health risks.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderLegionellales
FamilyLegionellaceae
GenusLegionella
SpeciesLegionella pneumophila
Strainstrain RH06

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Legionella pneumophila strain RH06
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAerobic
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Viridiplantae, Acanthamoeba castellanii
Cell arrangementSingles
SporulationNonsporulating
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Legionella pneumophila strain RH06

Gene Summary

Adenine Count

1128895 bp

Thymine Count

1137270 bp

Guanine Count

706077 bp

Cytosine Count

701230 bp

Genome Length

3673472 bp

Protein-coding Genes

3287 genes

Non-Coding Genes

51 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
holliday junction branch migration dna helicase ruvbDIZ44_14160Not AvailableNegative3050718 - 305174937901.0
rna polymerase subunit sigmaDIZ44_14165Not AvailableNegative3051875 - 305243822206.4
hypothetical proteinDIZ44_14170Not AvailableNegative3052539 - 305298217025.4
succinate dehydrogenase assembly factor 2DIZ44_14175Not AvailableNegative3052924 - 30531639488.45
folate-binding protein ygfzDIZ44_14180Not AvailablePositive3053220 - 305427840399.8
cytochrome bDIZ44_14185Not AvailableNegative3054309 - 305485720739.2
nad-glutamate dehydrogenaseDIZ44_14190Not AvailableNegative3054878 - 3059755185854.0
l,d-transpeptidaseDIZ44_14195Not AvailableNegative3059807 - 306029518110.8
succinate-semialdehyde dehydrogenaseDIZ44_14200Not AvailableNegative3060282 - 306167050911.6
phosphatidylcholine synthaseDIZ44_14205Not AvailablePositive3062013 - 306278029295.2

Displaying genes 2781 – 2790 of 3338 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Community-acquired pneumonia (cap)CausesPMC12584241
PneumoniaCausesPMC12584241
Legionnaires' diseaseCausesPMC2653234
Legionnaires' diseaseCausesPMC3014939
Legionnaires diseaseCausesPMC4379102
Mild diseasesCausesPMC5615607
CapCausesPMC7609860
Legionnaires diseaseCausesPMC8394066
LdCausesPMC8394066
PneumoniaCausesPMC8431511

Displaying health effects 1 – 10 of 45 in total