Helicobacter pylori strain B355

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain B355 is a Gram-negative bacterium characterized by its microaerophilic oxygen requirement and spirilla shape. This strain is associated with various hosts, including Homo sapiens, Gallus gallus, Aves, Primates, Mammalia, Amoeba, Rodentia, Cricetinae, and Thais. It exhibits a single cell arrangement and is non-motile, despite the presence of flagella. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic temperature range. H. pylori strain B355 is known for its pathogenicity in humans, contributing significantly to various gastrointestinal diseases. It is linked to chronic gastric inflammation, gastric ulcers, and more severe conditions such as gastric cancer and mucosa-associated lymphoid tissue (MALT) lymphoma. Additionally, the strain can cause functional dyspepsia and is implicated in duodenal ulcers and atrophic gastritis. The biological relationship of this strain is free-living, and it has a single replicon with a double membrane structure. The ecological significance of H. pylori strain B355 lies in its ability to colonize the gastric mucosa, where it can induce both symptomatic and asymptomatic inflammatory responses. Its presence in diverse host species suggests a complex evolutionary history and adaptability, which may influence the prevalence and outcomes of gastrointestinal diseases across different populations. Understanding the traits and health impacts of this strain can provide insights into its role in human health and disease.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain B355

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain B355
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain B355 scaffold_62, whole genome shotgun

Gene Summary

Adenine Count

504475 bp

Thymine Count

510907 bp

Guanine Count

321465 bp

Cytosine Count

323749 bp

Genome Length

1660633 bp

Protein-coding Genes

1482 genes

Non-Coding Genes

65 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
2,3,4,5-tetrahydropyridine-2,6-carboxylate n-succinyltransferaseDDP51_03335Not AvailablePositive665225 - 66643044150.1
hypothetical proteinDDP51_03340Not AvailablePositive666442 - 66750338232.0
duf262 domain-containing proteinDDP51_03345Not AvailablePositive667735 - 66978079712.9
flavodoxin family proteinDDP51_03350Not AvailableNegative669834 - 67041821577.8
ni/fe hydrogenaseDDP51_03355Not AvailablePositive670578 - 67173242329.4
hydrogenase 2 large subunitDDP51_03360Not AvailablePositive671742 - 67347864447.4
ni/fe-hydrogenase, b-type cytochrome subunitDDP51_03365Not AvailablePositive673491 - 67416525848.9
hyad/hybd family hydrogenase maturation endopeptidaseDDP51_03370Not AvailablePositive674162 - 67469819583.0
protein hydeDDP51_03375Not AvailablePositive674700 - 67623858361.5
hypothetical proteinDDP51_03380Not AvailableNegative676243 - 67665615935.4

Displaying genes 631 – 640 of 1547 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total