Helicobacter pylori strain B657-A1

Helicobacter pylori strain B657-A1 is a microaerophilic, Gram-negative bacterium characterized by a spirilla shape and the presence of flagella. It typically exists in a single arrangement and is adapted to a mesophilic temperature range, with an optimal growth temperature of 37°C. This strain is notable for its association with a variety of hosts, including Homo sapiens, Gallus gallus, other Aves, Primates, Mammalia, Amoeba, Rodentia, and Cricetinae. B657-A1 has a biotic relationship classified as free living, which suggests it can persist independently in its environment, although it is primarily host-associated. It possesses one replicon and two membranes, which are characteristic features of Gram-negative bacteria. The health effects associated with H. pylori strain B657-A1 are significant, as it has been linked to numerous gastrointestinal conditions, including chronic gastric inflammation, gastric ulcers, and various forms of gastric cancer, such as adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. Other conditions include functional dyspepsia, GERD, and atrophic gastritis. The pathogenicity of this strain primarily affects humans and underscores its importance in gastrointestinal disease. Given its diverse host range and the serious health implications of infections, H. pylori strain B657-A1 plays a crucial role in understanding the ecology of gastric pathogens and their impact on host health.