Helicobacter pylori strain 30908

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 30908 is a Gram-negative bacterium characterized by its microaerophilic oxygen requirement and spiral shape (spirilla). This organism typically exists as single cells and possesses flagella, which aids in its mobility. Strain 30908 is mesophilic, with an optimal growth temperature of 37°C. It has a biotic relationship that allows it to be free-living, yet it is primarily host-associated. The strain is notable for its pathogenicity in humans and its association with various hosts, including Homo sapiens, Gallus gallus (chickens), Aves (birds), Primates, Mammalia, Amoeba, Rodentia, and Cricetinae (hamsters). H. pylori strain 30908 is implicated in numerous health conditions, including chronic gastric inflammation, gastric cancer, gastric ulcers, and peptic ulcer disease. Other associated health issues include GERD, chronic gastritis, and MALT lymphoma. These conditions can lead to serious gastrointestinal diseases and significantly impact human health. The ability of H. pylori to cause such a wide range of gastrointestinal disorders highlights its ecological role as a pathogen in the human microbiome. Its presence can trigger inflammatory responses, contributing to chronic health issues. Understanding the traits of H. pylori strain 30908 can help elucidate its pathogenic mechanisms and inform strategies for managing infections and associated diseases.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 30908

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 30908
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 30908

Gene Summary

Adenine Count

506820 bp

Thymine Count

505699 bp

Guanine Count

325419 bp

Cytosine Count

322803 bp

Genome Length

1660741 bp

Protein-coding Genes

1577 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
30s ribosomal protein s21C2R84_04565Not AvailableNegative875490 - 8757028671.68
hypothetical proteinC2R84_04570Not AvailableNegative875803 - 87705349072.6
hypothetical proteinC2R84_04575Not AvailablePositive877226 - 8774478476.19
duf417 domain-containing proteinC2R84_04580Not AvailableNegative877495 - 87814223923.8
diaminopimelate epimeraseC2R84_04585Not AvailableNegative878255 - 87907630917.1
ai-2e family transporterC2R84_04590Not AvailablePositive879191 - 88023739822.1
radical sam proteinC2R84_04595Not AvailableNegative880381 - 88114829404.2
redox-regulated atpase ychfC2R84_04600Not AvailableNegative881268 - 88236840682.9
leucyl aminopeptidaseC2R84_04605Not AvailableNegative882370 - 88386054462.3
deda family proteinC2R84_04610Not AvailableNegative883908 - 88448622270.9

Displaying genes 871 – 880 of 1619 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total