Helicobacter pylori strain 30908

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 30908 is a Gram-negative bacterium characterized by its microaerophilic oxygen requirement and spiral shape (spirilla). This organism typically exists as single cells and possesses flagella, which aids in its mobility. Strain 30908 is mesophilic, with an optimal growth temperature of 37°C. It has a biotic relationship that allows it to be free-living, yet it is primarily host-associated. The strain is notable for its pathogenicity in humans and its association with various hosts, including Homo sapiens, Gallus gallus (chickens), Aves (birds), Primates, Mammalia, Amoeba, Rodentia, and Cricetinae (hamsters). H. pylori strain 30908 is implicated in numerous health conditions, including chronic gastric inflammation, gastric cancer, gastric ulcers, and peptic ulcer disease. Other associated health issues include GERD, chronic gastritis, and MALT lymphoma. These conditions can lead to serious gastrointestinal diseases and significantly impact human health. The ability of H. pylori to cause such a wide range of gastrointestinal disorders highlights its ecological role as a pathogen in the human microbiome. Its presence can trigger inflammatory responses, contributing to chronic health issues. Understanding the traits of H. pylori strain 30908 can help elucidate its pathogenic mechanisms and inform strategies for managing infections and associated diseases.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 30908

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 30908
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 30908

Gene Summary

Adenine Count

506820 bp

Thymine Count

505699 bp

Guanine Count

325419 bp

Cytosine Count

322803 bp

Genome Length

1660741 bp

Protein-coding Genes

1577 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
coa transferase subunit bC2R84_02200Not AvailableNegative417237 - 41786022216.2
succinyl-coa--3-ketoacid-coa transferaseC2R84_02205Not AvailableNegative417857 - 41855525414.9
acetyl-coa c-acyltransferaseC2R84_02210Not AvailableNegative418566 - 41974141214.1
3'-5' exonucleaseC2R84_02215Not AvailableNegative420023 - 42083531664.8
ferrous iron transport protein bC2R84_02220Not AvailablePositive420972 - 42290071441.6
ligand-gated channelC2R84_02225Not AvailablePositive423154 - 42545787462.6
flagellar biosynthetic protein flipC2R84_02230Not AvailableNegative425494 - 42624027875.6
flagellar biosynthesis protein flipC2R84_02235Not AvailableNegative426273 - 4263653412.46
bifunctional udp-n-acetylglucosamine diphosphorylase/glucosamine-1-phosphate n-acetyltransferase glmuC2R84_02240Not AvailablePositive426322 - 42762347875.1
pantothenate kinaseC2R84_02245Not AvailablePositive427780 - 42817514212.1

Displaying genes 421 – 430 of 1619 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total