Helicobacter pylori strain 31235

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 31235 is a microaerophilic, Gram-negative bacterium characterized by its spiral shape and presence of flagella. This strain is notable for its habitat, which is primarily host-associated, and it has a mobility characteristic classified as non-motile. The organism thrives optimally at a temperature of 37°C, fitting within the mesophilic temperature range. H. pylori strain 31235 possesses a unique cellular structure, featuring two membranes and a single replicon. It exhibits a free-living biotic relationship while primarily infecting various hosts, including Homo sapiens, Gallus gallus, and several other animal classes such as Aves and Primates. The health implications of H. pylori strain 31235 are significant, as it is implicated in a range of gastrointestinal diseases. These include chronic gastric inflammation, gastric ulcers, and various forms of gastric cancer, such as adenocarcinoma and mucosa-associated lymphoid tissue lymphoma. The presence of this strain can lead to a spectrum of conditions from asymptomatic mucosal inflammatory responses to severe diseases like peptic ulcer disease and functional dyspepsia. The ecological insight from H. pylori strain 31235 highlights its role in the human microbiome, particularly in relation to gastric health. Its pathogenicity underscores the importance of understanding host-bacterium interactions, as the strain's presence can lead to serious health outcomes, illustrating its significant impact on both individual health and broader public health concerns.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 31235

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 31235
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 31235

Gene Summary

Adenine Count

499251 bp

Thymine Count

504445 bp

Guanine Count

315127 bp

Cytosine Count

322688 bp

Genome Length

1641511 bp

Protein-coding Genes

1508 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinC2R86_05970Not AvailableNegative1171336 - 117331877147.1
pyridoxal phosphate-dependent aminotransferaseC2R86_05975Not AvailableNegative1173467 - 117463942925.0
hypothetical proteinC2R86_05980Not AvailableNegative1174799 - 117561130375.2
glycerol-3-phosphate dehydrogenaseC2R86_05990Not AvailableNegative1180751 - 118205249358.4
oxygen-independent coproporphyrinogen iii oxidaseC2R86_05995Not AvailableNegative1182049 - 118342253303.9
duf2603 domain-containing proteinC2R86_06000Not AvailableNegative1183422 - 118393720110.9
chorismate synthaseC2R86_06005Not AvailableNegative1183974 - 118507140020.2
ribonuclease iiiC2R86_06010Not AvailableNegative1185068 - 118579027430.4
ribonuclease hiC2R86_06015Not AvailableNegative1185799 - 118623016263.5
hypothetical proteinC2R86_06020Not AvailableNegative1186217 - 118723339394.1

Displaying genes 1111 – 1120 of 1550 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total