Helicobacter pylori strain 32

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 32 is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and presence of flagella. It is primarily found in host-associated environments, specifically within various hosts, including Homo sapiens, Gallus gallus, Aves, Primates, Mammalia, Amoeba, Rodentia, Cricetinae, and Thais. The bacterium exhibits a single cell arrangement and has a mesophilic temperature range, with an optimal growth temperature of 37°C. This strain has significant pathogenic implications for human health, being associated with numerous gastrointestinal diseases. It can lead to chronic gastric inflammation, peptic ulcer disease, and various forms of cancer, including gastric cancer and mucosa-associated lymphoid tissue lymphoma. Additionally, it may cause functional dyspepsia, atrophic gastritis, and intestinal metaplasia, among other conditions. The range of diseases linked to H. pylori strain 32 underscores its role as a major pathogen in the gastrointestinal tract and highlights the complexity of its interactions with the host. The biotic relationship of H. pylori strain 32 is classified as free-living, suggesting its capacity to thrive within the host's environment. However, its pathogenicity is predominantly human-centric, emphasizing its potential impact on public health. Understanding the ecological niche and health effects of this strain can enhance prevention and treatment strategies for associated gastrointestinal diseases, particularly those leading to cancer.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 32

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 32
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 32

Gene Summary

Adenine Count

508394 bp

Thymine Count

505836 bp

Guanine Count

323304 bp

Cytosine Count

322032 bp

Genome Length

1659566 bp

Protein-coding Genes

1481 genes

Non-Coding Genes

41 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
acetone carboxylase subunit betaC2R96_00355Not AvailableNegative68574 - 7071578524.2
acetone carboxylase subunit betaC2R96_00370Not AvailablePositive72620 - 7476178524.2
acetone carboxylase subunit alphaC2R96_00375Not AvailablePositive74773 - 7707086503.6
acetone carboxylase subunit gammaC2R96_00380Not AvailablePositive77081 - 7758719864.9
hypothetical proteinC2R96_00385Not AvailablePositive77901 - 7892938821.2
diacylglycerol kinaseC2R96_00390Not AvailablePositive78922 - 7930814468.9
dna gyrase subunit aC2R96_00395Not AvailablePositive79324 - 8181993158.5
hypothetical proteinC2R96_00400Not AvailablePositive81816 - 8229218372.6
sigma-54-dependent fis family transcriptional regulatorC2R96_00405Not AvailablePositive82289 - 8343443447.9
excinuclease abc subunit aC2R96_00415Not AvailableNegative84660 - 87467104073.0

Displaying genes 71 – 80 of 1522 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total