Helicobacter pylori strain 29:2_single

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 29:2_single is a microaerophilic, Gram-negative bacterium characterized by its spirilla shape and presence of flagella. This strain is noted for its habitat within various hosts, including Homo sapiens, Gallus gallus, Aves, Primates, Mammalia, Amoeba, Rodentia, and Cricetinae. It exhibits a single replicon and has two membranes, aligning with its classification as a free-living bacterium. The optimal growth temperature for strain 29:2_single is 37°C, placing it within the mesophilic temperature range. Its cellular arrangement is predominantly singles, and it exhibits no mobility, which is a notable characteristic for a bacterium typically associated with gastric conditions. Strain 29:2_single is linked to a multitude of health effects, particularly concerning chronic gastric conditions. It is associated with various diseases, including chronic gastric inflammation, peptic ulcer disease, and gastric cancer. The strain contributes to the development of gastric ulcers, mucosa-associated lymphoid tissue lymphoma, and other gastrointestinal diseases, leading to significant health concerns such as functional dyspepsia and atrophic gastritis. The pathogenicity of this strain in humans underscores its relevance in clinical microbiology and public health. Understanding its biological and ecological interactions with host organisms can aid in developing targeted treatments for the various gastric and intestinal diseases it causes, highlighting the importance of recognizing Helicobacter pylori as a significant pathogen in human health.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 29:2_single

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 29:2_single
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 29:2_single

Gene Summary

Adenine Count

487988 bp

Thymine Count

484223 bp

Guanine Count

309727 bp

Cytosine Count

314303 bp

Genome Length

1596241 bp

Protein-coding Genes

1478 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
sel1-like repeat protein hcpaC2S30_06790Not AvailableNegative1323661 - 132441327279.9
succinyl-diaminopimelate desuccinylaseC2S30_06800Not AvailableNegative1324873 - 132609945386.6
trna uridine-5-carboxymethylaminomethyl(34) synthesis enzyme mnmgC2S30_06805Not AvailableNegative1326110 - 132797569576.9
carboxylate transporterC2S30_06810Not AvailablePositive1328071 - 132972959836.3
phosphatidate cytidylyltransferaseC2S30_06815Not AvailablePositive1329742 - 133054228851.1
1-deoxy-d-xylulose-5-phosphate reductoisomeraseC2S30_06820Not AvailablePositive1330543 - 133164340351.4
hypothetical proteinC2S30_06825Not AvailablePositive1331677 - 13318566468.38
ybhb/ybcl family raf kinase inhibitor-like proteinC2S30_06830Not AvailableNegative1331930 - 133248120701.9
dna-binding proteinC2S30_06835Not AvailablePositive1332625 - 133308617810.7
cysteine desulfurase, nifs familyC2S30_06840Not AvailablePositive1333260 - 133442342432.0

Displaying genes 1281 – 1290 of 1520 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total