Helicobacter pylori strain 55:5

Gram-negativeSpirillaNon-motileMicroaerophilic

Kingdom

Pseudomonadati

Phylum

Campylobacterota

Class

Epsilonproteobacteria

Order

Campylobacterales

Family

Helicobacteraceae

Genus

Helicobacter

Description

Helicobacter pylori strain 55:5 is a gram-negative bacterium that is microaerophilic and exhibits a spirilla shape. This organism is characterized by its presence of flagella, which allows for mobility, although it is known to exist primarily as single cells. Strain 55:5 has a mesophilic temperature range, with an optimal growth temperature of 37 degrees Celsius. In terms of its ecological niche, H. pylori strain 55:5 is host-associated, predominantly found in Homo sapiens, as well as in various animal hosts including Gallus gallus, Aves, Primates, Mammalia, Amoeba, Rodentia, Cricetinae, and Thais. The bacterium has a biotic relationship classified as free-living, indicating it can survive in diverse environments associated with its hosts. The pathogenicity of H. pylori strain 55:5 is notably significant, as it is linked to a variety of gastrointestinal diseases. These include chronic gastric inflammation, gastric ulcers, and various forms of gastric cancer, such as gastric carcinoma and mucosa-associated lymphoid tissue lymphoma. It is also associated with conditions like GERD, chronic gastritis, and functional dyspepsia. The presence of H. pylori in humans and its potential to cause severe gastric conditions underscore its importance in medical microbiology. Understanding the specific traits of strain 55:5 can aid in developing targeted strategies for managing infections and related diseases, highlighting the need for ongoing research into its pathogenic mechanisms and host interactions.

Taxonomy

KingdomPseudomonadati
PhylumCampylobacterota
ClassEpsilonproteobacteria
OrderCampylobacterales
FamilyHelicobacteraceae
GenusHelicobacter
SpeciesHelicobacter pylori
Strainstrain 55:5

Profile

Physiology
Gram staining propertiesNegative
ShapeSpirilla
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Helicobacter pylori strain 55:5
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsMicroaerophilic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Aves
Cell arrangementSingles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Helicobacter pylori strain 55:5

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1591 genes

Non-Coding Genes

42 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cyclic pyranopterin monophosphate synthase moacC2S44_01705Not AvailableNegative312834 - 31331017262.3
molybdopterin adenylyltransferaseC2S44_01710Not AvailableNegative313319 - 31384919710.1
molybdenum cofactor biosynthesis protein moaeC2S44_01715Not AvailableNegative313862 - 31429916474.1
molybdopterin synthase sulfur carrier subunitC2S44_01720Not AvailableNegative314300 - 3145218092.87
gtp cyclohydrolase iiC2S44_01725Not AvailableNegative314599 - 31517721691.2
duf3943 domain-containing proteinC2S44_01730Not AvailableNegative315266 - 31610532166.8
bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/gtp cyclohydrolase iiC2S44_01735Not AvailableNegative316194 - 31722838851.9
lipooligosaccharide 5g8 epitope biosynthesis-associated protein (lex2b)C2S44_01740Not AvailableNegative317301 - 31814632680.2
metalloproteaseC2S44_01745Not AvailablePositive318228 - 31884824059.6
ligand-gated channelC2S44_01750Not AvailableNegative318851 - 32122989792.6

Displaying genes 321 – 330 of 1633 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Chronic gastric inflammationCausesPMC10226649
Gastric cancerCausesPMC10226649
Gastric ulcersCausesPMC10420633
Stomach carcinomaCausesPMC10420633
UlcersCausesPMC10420633
AdenocarcinomaCausesPMC10420633
Mucosa-associated lymphoid tissue lymphomaCausesPMC10420633
GerdCausesPMC10712878
GastritisCausesPMC10712878
Gastric cancerCausesPMC10732068

Displaying health effects 1 – 10 of 94 in total