Escherichia coli strain GER_MD14_1505_Eco_038

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain GER_MD14_1505_Eco_038 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. This strain is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It is mesophilic, with an optimal growth temperature of 37°C, which corresponds to the normal human body temperature. GER_MD14_1505_Eco_038 is host-associated and has a diverse range of hosts, including Homo sapiens, various domesticated animals such as Gallus gallus (chickens), Bos taurus (cattle), and Sus scrofa (pigs), as well as numerous other vertebrates and invertebrates. This bacterium can establish free-living biotic relationships, indicating its capability to survive outside of host organisms under certain conditions. The strain is associated with a wide array of health effects, particularly in humans, where it is known to cause urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions such as septicemia and neonatal meningitis. Other health issues linked to this strain include diarrheal diseases, colibacillosis, and complications such as hemolytic uremic syndrome (HUS), highlighting its pathogenicity. The extensive host range and the diverse pathological effects associated with GER_MD14_1505_Eco_038 underscore its ecological versatility and potential impact on both human and animal health. Understanding its pathogenic mechanisms and transmission dynamics can provide insights into preventing infections and managing outbreaks related to this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain GER_MD14_1505_Eco_038

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain GER_MD14_1505_Eco_038
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain GER_MD14_1505_Eco_038


Gene Summary

Adenine Count

1319978 bp

Thymine Count

1323505 bp

Guanine Count

1363372 bp

Cytosine Count

1329055 bp

Genome Length

5335910 bp

Protein-coding Genes

5105 genes

Non-Coding Genes

282 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinC6B13_01830Not AvailableNegative381266 - 3814185689.89
Hypothetical proteinC6B13_01835Not AvailablePositive381436 - 3816277462.05
succinate dehydrogenaseC6B13_01840Not AvailablePositive381689 - 3818356054.64
Putative outer membrane lipoproteinC6B13_01845Not AvailablePositive381938 - 38245617706.1
Hypothetical proteinC6B13_01850Not AvailablePositive382472 - 38301120279.5
AttlNot AvailableNot AvailablePositive383104 - 383120Not Available
Tail proteinC6B13_01855Not AvailableNegative383231 - 38371318108.3
Putative endolysinC6B13_01860Not AvailableNegative383710 - 38433922982.3
Putative holinC6B13_01865Not AvailableNegative384329 - 38463711437.3
Hypothetical proteinC6B13_01870Not AvailableNegative384624 - 38502814263.6

Displaying genes 1 – 10 of 5387 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total