Escherichia coli strain NCDC 62-57 NalR-Br23R2

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain NCDC 62-57 NalR-Br23R2 is a Gram-negative, rod-shaped bacterium that demonstrates mobility due to the presence of flagella. It is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. This strain is mesophilic, with an optimal growth temperature of 37°C, and it typically exists in pairs or as single cells. NCDC 62-57 NalR-Br23R2 is associated with a wide variety of hosts, including Homo sapiens, various domesticated animals like Gallus gallus (chickens), Bos taurus (cattle), and Canis lupus familiaris (dogs), as well as several other vertebrate and invertebrate species. The strain exhibits a free-living biotic relationship, indicating its ability to exist independently in its habitat. This strain is notable for its pathogenicity in humans, being linked to numerous health issues such as urinary tract infections (UTIs), gastrointestinal infections, and more severe conditions including septicemia and hemorrhagic colitis. The diverse array of health effects associated with NCDC 62-57 NalR-Br23R2 emphasizes its role in foodborne infections, neonatal meningitis, and complications related to pregnancy, among others. The ecological significance of this strain lies in its adaptability to various hosts and environments, potentially contributing to its role in both commensal and pathogenic relationships. Understanding the characteristics and impacts of NCDC 62-57 NalR-Br23R2 can aid in developing strategies to mitigate its pathogenic effects in clinical settings.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain NCDC 62-57 NalR-Br23R2

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain NCDC 62-57 NalR-Br23R2
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain NCDC 62-57 NalR-Br23R2

Gene Summary

Adenine Count

1391279 bp

Thymine Count

1390623 bp

Guanine Count

1391996 bp

Cytosine Count

1434516 bp

Genome Length

5608414 bp

Protein-coding Genes

5345 genes

Non-Coding Genes

502 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
sulfate abc transporter permeaseC5715_17755Not AvailableNegative3344065 - 334494032539.6
sulfate abc transporter permeaseC5715_17760Not AvailableNegative3344940 - 334577330293.6
sulfate abc transporter substrate-binding proteinC5715_17765Not AvailableNegative3345773 - 334678937629.6
nad(p)-dependent oxidoreductaseC5715_17770Not AvailableNegative3346960 - 334775127865.7
murr/rpir family transcriptional regulatorC5715_17775Not AvailableNegative3347880 - 334873731399.8
n-acetylmuramic acid 6-phosphate etheraseC5715_17780Not AvailablePositive3348909 - 334980531042.7
pts n-acetylmuramic acid transporter subunits iibcC5715_17785Not AvailablePositive3349809 - 335123349813.1
penicillin binding protein pbp4bC5715_17790Not AvailablePositive3351238 - 335253947496.8
deferrochelatase/peroxidaseC5715_17795Not AvailableNegative3352597 - 335349633072.1
rpoe-regulated lipoproteinC5715_17800Not AvailableNegative3353592 - 335416720829.6

Displaying genes 3711 – 3720 of 5847 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total