Escherichia coli strain JL_F20_1

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain JL_F20_1 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and exhibits mobility due to the presence of flagella. This strain is primarily host-associated, having been identified in a variety of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and Bos taurus (cattle), among others. It exists in pairs or singles and thrives optimally at 37°C, indicating that it is mesophilic in nature. The strain has a single replicon and is characterized by a double-membrane structure, typical of Gram-negative bacteria. JL_F20_1 has been implicated in a wide range of health effects, particularly in humans, where it is associated with urinary tract infections (UTIs), gastrointestinal infections, and severe conditions such as hemorrhagic colitis and hemolytic uremic syndrome (HUS). These health concerns highlight its pathogenic potential, particularly in causing urinary and intestinal diseases. Ecologically, the diverse range of hosts associated with JL_F20_1 suggests that it plays a versatile role in various environments, affecting both animal and human health. Its free-living nature indicates that it can survive outside of a host, potentially leading to foodborne infections and outbreaks. The ability to thrive in multiple hosts and its associated health implications underscore the importance of monitoring and understanding this strain within both clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strainstrain JL_F20_1

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli strain JL_F20_1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain JL_F20_1 NODE_197_length_317_cov_0.357895,

Gene Summary

Adenine Count

1363620 bp

Thymine Count

1365332 bp

Guanine Count

1392194 bp

Cytosine Count

1395992 bp

Genome Length

5517138 bp

Protein-coding Genes

5208 genes

Non-Coding Genes

362 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Putative tail componentC5P44_27360Not AvailableNegative5240747 - 524139422674.5
Tail fiber componentC5P44_27365Not AvailableNegative5241292 - 524203528396.4
Putative minor tail proteinC5P44_27370Not AvailableNegative5242041 - 524273925609.8
Putative minor tail proteinC5P44_27375Not AvailableNegative5242749 - 524307812530.1
Putative tail proteinC5P44_27380Not AvailableNegative5243078 - 5246134112140.0
Putative minor tail proteinC5P44_27385Not AvailableNegative5246106 - 524643512350.6
Minor tail proteinC5P44_27390Not AvailableNegative5246444 - 524683014212.8
Major tail proteinC5P44_27395Not AvailableNegative5246890 - 524763325698.2
Putative tail componentC5P44_27400Not AvailableNegative5247644 - 524804515045.8
Putative tail componentC5P44_27405Not AvailableNegative5248042 - 524862021549.7

Displaying genes 271 – 280 of 5570 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total